I SPI1 something needed for B cells

In this issue, Le Coz et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20201750) describe a novel immunodeficiency syndrome caused by mutations in SPI1. Through a series of in-depth studies, the authors provide insights into how SPI1 affects blood lineage specification, highlighting the import...

Descripción completa

Detalles Bibliográficos
Autores principales: Wahlster, Lara, Sankaran, Vijay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126978/
https://www.ncbi.nlm.nih.gov/pubmed/33978700
http://dx.doi.org/10.1084/jem.20210572
_version_ 1783693868400640000
author Wahlster, Lara
Sankaran, Vijay G.
author_facet Wahlster, Lara
Sankaran, Vijay G.
author_sort Wahlster, Lara
collection PubMed
description In this issue, Le Coz et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20201750) describe a novel immunodeficiency syndrome caused by mutations in SPI1. Through a series of in-depth studies, the authors provide insights into how SPI1 affects blood lineage specification, highlighting the important role of master transcription factors as cellular fate determinants.
format Online
Article
Text
id pubmed-8126978
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-81269782022-01-05 I SPI1 something needed for B cells Wahlster, Lara Sankaran, Vijay G. J Exp Med Insights In this issue, Le Coz et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20201750) describe a novel immunodeficiency syndrome caused by mutations in SPI1. Through a series of in-depth studies, the authors provide insights into how SPI1 affects blood lineage specification, highlighting the important role of master transcription factors as cellular fate determinants. Rockefeller University Press 2021-05-12 /pmc/articles/PMC8126978/ /pubmed/33978700 http://dx.doi.org/10.1084/jem.20210572 Text en © 2021 Wahlster and Sankaran http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Wahlster, Lara
Sankaran, Vijay G.
I SPI1 something needed for B cells
title I SPI1 something needed for B cells
title_full I SPI1 something needed for B cells
title_fullStr I SPI1 something needed for B cells
title_full_unstemmed I SPI1 something needed for B cells
title_short I SPI1 something needed for B cells
title_sort i spi1 something needed for b cells
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126978/
https://www.ncbi.nlm.nih.gov/pubmed/33978700
http://dx.doi.org/10.1084/jem.20210572
work_keys_str_mv AT wahlsterlara ispi1somethingneededforbcells
AT sankaranvijayg ispi1somethingneededforbcells

Ejemplares similares