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Knockout of the CEP290 gene in human induced pluripotent stem cells
CEP290 is a principal component of the primary cilium and is important for the proper function of ciliated cells. CEP290 mutations have been linked to numerous ciliopathies, with a wide range of phenotypic severities, but with poor genotype:phenotype correlation. Here we have used CRISPR/Cas9 techno...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127132/ https://www.ncbi.nlm.nih.gov/pubmed/33626495 http://dx.doi.org/10.1016/j.scr.2021.102243 |