Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): statistical analysis plan for a randomised controlled trial assessing the effectiveness of peri-articular liposomal bupivacaine plus bupivacaine hydrochloride compared with bupivacaine hydrochloride alone

BACKGROUND: Up to three quarters of surgical patients receive inadequate pain relief, with 40% of patients reporting severe pain following knee replacement, which may indicate the current pain relief strategies using opiate-based analgesia cannot achieve patient satisfaction. Liposomal bupivacaine i...

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Detalles Bibliográficos
Autores principales: Stokes, Jamie R., Wang, Ariel, Poulton, Lisa, Rombach, Ines, Pandit, Hemant, Knight, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127239/
https://www.ncbi.nlm.nih.gov/pubmed/34001205
http://dx.doi.org/10.1186/s13063-021-05293-7

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