An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

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BACKGROUND: While genome-wide associations studies (GWAS) have successfully elucidated the genetic architecture of complex human traits and diseases, understanding mechanisms that lead from genetic variation to pathophysiology remains an important challenge. Methods are needed to systematically brid...

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Detalles Bibliográficos
Autores principales: Wang, Liuyang, Balmat, Thomas J., Antonia, Alejandro L., Constantine, Florica J., Henao, Ricardo, Burke, Thomas W., Ingham, Andy, McClain, Micah T., Tsalik, Ephraim L., Ko, Emily R., Ginsburg, Geoffrey S., DeLong, Mark R., Shen, Xiling, Woods, Christopher W., Hauser, Elizabeth R., Ko, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127495/
https://www.ncbi.nlm.nih.gov/pubmed/34001247
http://dx.doi.org/10.1186/s13073-021-00904-z
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