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Cardiovascular diseases burden in COVID-19: About a Moroccan experience

INTRODUCTION: COVID-19 has been responsive of a worldwide pandemic primarily causing respiratory illness. Cardiovascular involvement can occur through several mechanisms. SARS-COV-2 may trigger a cytokine storm resulting in hyperinflammatory response and multiorgan damage. High rates of cardiovascul...

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Autores principales: Boutaleb, A.M., Benouna, M.E.G., Arous, S., Drighil, A., Habbal, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS 2021
Materias:
306
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127552/
http://dx.doi.org/10.1016/j.acvdsp.2021.04.138
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author Boutaleb, A.M.
Benouna, M.E.G.
Arous, S.
Drighil, A.
Habbal, R.
author_facet Boutaleb, A.M.
Benouna, M.E.G.
Arous, S.
Drighil, A.
Habbal, R.
author_sort Boutaleb, A.M.
collection PubMed
description INTRODUCTION: COVID-19 has been responsive of a worldwide pandemic primarily causing respiratory illness. Cardiovascular involvement can occur through several mechanisms. SARS-COV-2 may trigger a cytokine storm resulting in hyperinflammatory response and multiorgan damage. High rates of cardiovascular diseases (CVD) have been reported during the COVID-19 global pandemic. Preexisting CVD is associated with increased mortality in COVID-19 patients. Furthermore, SARS-COV-2 seems to promote the development of various CVD. OBJECTIVE: The aim of this study is to relate cardiovascular diseases distribution among patients screened for COVID-19. METHOD: It relies on a retrospective study conducted between September 2020 and February 2021 including patients diagnosed for COVID-19 in the cardiology department of IBN ROCHD University Hospital. RESULTS: Twelve patients were included. Among these patients, nine had PCR+ and three had positive serology testing (IGg+). Mean age of the population was 48 years old with male predominance (sex ratio = 1.4). Three patients had medical history of hypertension, two of them were diabetic and five patients were chronic smokers. During hospitalization, seven patients reported cough, while six had fever. Main clinical presentation was ACS, followed by myopericarditis, decompensated heart failure and pulmonary embolism. Mean CRP was 35.45 and mean hsTn was 7401 pg/L. CONCLUSION: This study highlights the variety of diseases that may be caused by the SARS-COV2. Given the cardiovascular diseases burden during COVID-19 global pandemic, further researches are required to understand the incidence, mechanisms and outcomes of various CV manifestations in COVID-19 patients.
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spelling pubmed-81275522021-05-18 Cardiovascular diseases burden in COVID-19: About a Moroccan experience Boutaleb, A.M. Benouna, M.E.G. Arous, S. Drighil, A. Habbal, R. Archives of Cardiovascular Diseases. Supplements 306 INTRODUCTION: COVID-19 has been responsive of a worldwide pandemic primarily causing respiratory illness. Cardiovascular involvement can occur through several mechanisms. SARS-COV-2 may trigger a cytokine storm resulting in hyperinflammatory response and multiorgan damage. High rates of cardiovascular diseases (CVD) have been reported during the COVID-19 global pandemic. Preexisting CVD is associated with increased mortality in COVID-19 patients. Furthermore, SARS-COV-2 seems to promote the development of various CVD. OBJECTIVE: The aim of this study is to relate cardiovascular diseases distribution among patients screened for COVID-19. METHOD: It relies on a retrospective study conducted between September 2020 and February 2021 including patients diagnosed for COVID-19 in the cardiology department of IBN ROCHD University Hospital. RESULTS: Twelve patients were included. Among these patients, nine had PCR+ and three had positive serology testing (IGg+). Mean age of the population was 48 years old with male predominance (sex ratio = 1.4). Three patients had medical history of hypertension, two of them were diabetic and five patients were chronic smokers. During hospitalization, seven patients reported cough, while six had fever. Main clinical presentation was ACS, followed by myopericarditis, decompensated heart failure and pulmonary embolism. Mean CRP was 35.45 and mean hsTn was 7401 pg/L. CONCLUSION: This study highlights the variety of diseases that may be caused by the SARS-COV2. Given the cardiovascular diseases burden during COVID-19 global pandemic, further researches are required to understand the incidence, mechanisms and outcomes of various CV manifestations in COVID-19 patients. Published by Elsevier Masson SAS 2021-05 2021-05-17 /pmc/articles/PMC8127552/ http://dx.doi.org/10.1016/j.acvdsp.2021.04.138 Text en Copyright © 2021 Published by Elsevier Masson SAS. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle 306
Boutaleb, A.M.
Benouna, M.E.G.
Arous, S.
Drighil, A.
Habbal, R.
Cardiovascular diseases burden in COVID-19: About a Moroccan experience
title Cardiovascular diseases burden in COVID-19: About a Moroccan experience
title_full Cardiovascular diseases burden in COVID-19: About a Moroccan experience
title_fullStr Cardiovascular diseases burden in COVID-19: About a Moroccan experience
title_full_unstemmed Cardiovascular diseases burden in COVID-19: About a Moroccan experience
title_short Cardiovascular diseases burden in COVID-19: About a Moroccan experience
title_sort cardiovascular diseases burden in covid-19: about a moroccan experience
topic 306
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127552/
http://dx.doi.org/10.1016/j.acvdsp.2021.04.138
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