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SMAD4 Expression in Renal Cell Carcinomas Correlates With a Stem-Cell Phenotype and Poor Clinical Outcomes

Renal cell carcinoma (RCC) is the most lethal neoplasm of common urologic cancers with poor prognoses. SMAD4 has a principal role in TGF-β (Transformis growth factorβ)-induced epithelial to mesenchymal transition (EMT) as a key factor in gaining cancer stem cell (CSC) features and tumor aggressivene...

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Detalles Bibliográficos
Autores principales:	Rasti, Arezoo, Madjd, Zahra, Saeednejad Zanjani, Leili, Babashah, Sadegh, Abolhasani, Maryam, Asgari, Mojgan, Mehrazma, Mitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127783/ https://www.ncbi.nlm.nih.gov/pubmed/34012911 http://dx.doi.org/10.3389/fonc.2021.581172

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