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A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression

Despite the well-accepted view that chronic inflammation contributes to the pathogenesis of Duchenne muscular dystrophy (DMD), the function and regulation of eosinophils remain an unclear facet of type II innate immunity in dystrophic muscle. We report the observation that group 2 innate lymphoid ce...

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Detalles Bibliográficos
Autores principales: Kastenschmidt, Jenna M., Coulis, Gerald, Farahat, Philip K., Pham, Phillip, Rios, Rodolfo, Cristal, Therese T., Mannaa, Ali H., Ayer, Rachel E., Yahia, Rayan, Deshpande, Archis A., Hughes, Brandon S., Savage, Adam K., Giesige, Carlee R., Harper, Scott Q., Locksley, Richard M., Mozaffar, Tahseen, Villalta, S. Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127948/
https://www.ncbi.nlm.nih.gov/pubmed/33852849
http://dx.doi.org/10.1016/j.celrep.2021.108997