Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice

One of the proposed strategies for the development of a more efficient HIV-1 vaccine is based on the identification of proteins binding to a paratope of chosen broadly neutralizing antibody (bNAb) that will mimic cognate HIV-1 Env (glyco)protein epitope and could be used as potent immunogens for ind...

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Detalles Bibliográficos
Autores principales: Kuchař, Milan, Kosztyu, Petr, Daniel Lišková, Veronika, Černý, Jiří, Petroková, Hana, Vróblová, Eliška, Malý, Michal, Vaňková, Lucie, Křupka, Michal, Rašková Kafková, Leona, Turánek Knotigová, Pavlína, Dušková, Jarmila, Dohnálek, Jan, Mašek, Josef, Turánek, Jaroslav, Raška, Milan, Malý, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128222/
https://www.ncbi.nlm.nih.gov/pubmed/33993840
http://dx.doi.org/10.1080/21505594.2021.1920251

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