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MADRID+90 study on factors associated with longevity: Study design and preliminary data
The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represen...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128242/ https://www.ncbi.nlm.nih.gov/pubmed/33999936 http://dx.doi.org/10.1371/journal.pone.0251796 |
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author | Fernández-Blázquez, Miguel A. del Ser, Teodoro Frades-Payo, Belén Ávila-Villanueva, Marina Valentí-Soler, Meritxell Benítez-Robredo, María T. Bermejo-Aguña, Antonio Pedrero-Pérez, Eduardo J. Quilis-Sancho, Javier Pastor, Ana B. Fernández-Garrido, Concepción Morales-Alonso, Sara Diaz-Olalla, José M. Santos, Nadine Correia Maestú, Fernando Gómez-Ramírez, Jaime |
author_facet | Fernández-Blázquez, Miguel A. del Ser, Teodoro Frades-Payo, Belén Ávila-Villanueva, Marina Valentí-Soler, Meritxell Benítez-Robredo, María T. Bermejo-Aguña, Antonio Pedrero-Pérez, Eduardo J. Quilis-Sancho, Javier Pastor, Ana B. Fernández-Garrido, Concepción Morales-Alonso, Sara Diaz-Olalla, José M. Santos, Nadine Correia Maestú, Fernando Gómez-Ramírez, Jaime |
author_sort | Fernández-Blázquez, Miguel A. |
collection | PubMed |
description | The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represents an opportunity to explore which lifestyle factors are associated with healthy aging and which with the emergence of age-related diseases, especially Alzheimer’s type dementia. The project “Factors associated with healthy and pathologically aging in a sample of elderly people over 90 in the city of Madrid” (MADRID+90) brings together a multidisciplinary research team in neurodegenerative diseases that includes experts in epidemiology, neurology, neuropsychology, neuroimaging and computational neuroscience. In the first phase of the project, a stratified random sampling was carried out according to the census of the city of Madrid followed by a survey conducted on 191 people aged 90 and over. This survey gathered information on demographics, clinical data, lifestyles and cognitive status. Here, the main results of that survey are showed. The second phase of the project aims to characterize individual trajectories in the course of either healthy and pathological aging, from a group of 50 subjects over 90 who will undergo a comprehensive clinical examination comprised of neurological and cognitive testing, MRI and EEG. The ultimate goal of the project is to characterize the biophysical and clinical profiles of a population that tends to receive little attention in the literature. A better understanding of the rapidly increasing group of nonagenarians will also help to design new policies that minimize the impact and future social and economic consequences of rapidly aging societies. |
format | Online Article Text |
id | pubmed-8128242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-81282422021-05-27 MADRID+90 study on factors associated with longevity: Study design and preliminary data Fernández-Blázquez, Miguel A. del Ser, Teodoro Frades-Payo, Belén Ávila-Villanueva, Marina Valentí-Soler, Meritxell Benítez-Robredo, María T. Bermejo-Aguña, Antonio Pedrero-Pérez, Eduardo J. Quilis-Sancho, Javier Pastor, Ana B. Fernández-Garrido, Concepción Morales-Alonso, Sara Diaz-Olalla, José M. Santos, Nadine Correia Maestú, Fernando Gómez-Ramírez, Jaime PLoS One Research Article The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represents an opportunity to explore which lifestyle factors are associated with healthy aging and which with the emergence of age-related diseases, especially Alzheimer’s type dementia. The project “Factors associated with healthy and pathologically aging in a sample of elderly people over 90 in the city of Madrid” (MADRID+90) brings together a multidisciplinary research team in neurodegenerative diseases that includes experts in epidemiology, neurology, neuropsychology, neuroimaging and computational neuroscience. In the first phase of the project, a stratified random sampling was carried out according to the census of the city of Madrid followed by a survey conducted on 191 people aged 90 and over. This survey gathered information on demographics, clinical data, lifestyles and cognitive status. Here, the main results of that survey are showed. The second phase of the project aims to characterize individual trajectories in the course of either healthy and pathological aging, from a group of 50 subjects over 90 who will undergo a comprehensive clinical examination comprised of neurological and cognitive testing, MRI and EEG. The ultimate goal of the project is to characterize the biophysical and clinical profiles of a population that tends to receive little attention in the literature. A better understanding of the rapidly increasing group of nonagenarians will also help to design new policies that minimize the impact and future social and economic consequences of rapidly aging societies. Public Library of Science 2021-05-17 /pmc/articles/PMC8128242/ /pubmed/33999936 http://dx.doi.org/10.1371/journal.pone.0251796 Text en © 2021 Fernández-Blázquez et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Fernández-Blázquez, Miguel A. del Ser, Teodoro Frades-Payo, Belén Ávila-Villanueva, Marina Valentí-Soler, Meritxell Benítez-Robredo, María T. Bermejo-Aguña, Antonio Pedrero-Pérez, Eduardo J. Quilis-Sancho, Javier Pastor, Ana B. Fernández-Garrido, Concepción Morales-Alonso, Sara Diaz-Olalla, José M. Santos, Nadine Correia Maestú, Fernando Gómez-Ramírez, Jaime MADRID+90 study on factors associated with longevity: Study design and preliminary data |
title | MADRID+90 study on factors associated with longevity: Study design and preliminary data |
title_full | MADRID+90 study on factors associated with longevity: Study design and preliminary data |
title_fullStr | MADRID+90 study on factors associated with longevity: Study design and preliminary data |
title_full_unstemmed | MADRID+90 study on factors associated with longevity: Study design and preliminary data |
title_short | MADRID+90 study on factors associated with longevity: Study design and preliminary data |
title_sort | madrid+90 study on factors associated with longevity: study design and preliminary data |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128242/ https://www.ncbi.nlm.nih.gov/pubmed/33999936 http://dx.doi.org/10.1371/journal.pone.0251796 |
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