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MADRID+90 study on factors associated with longevity: Study design and preliminary data

The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represen...

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Autores principales: Fernández-Blázquez, Miguel A., del Ser, Teodoro, Frades-Payo, Belén, Ávila-Villanueva, Marina, Valentí-Soler, Meritxell, Benítez-Robredo, María T., Bermejo-Aguña, Antonio, Pedrero-Pérez, Eduardo J., Quilis-Sancho, Javier, Pastor, Ana B., Fernández-Garrido, Concepción, Morales-Alonso, Sara, Diaz-Olalla, José M., Santos, Nadine Correia, Maestú, Fernando, Gómez-Ramírez, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128242/
https://www.ncbi.nlm.nih.gov/pubmed/33999936
http://dx.doi.org/10.1371/journal.pone.0251796
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author Fernández-Blázquez, Miguel A.
del Ser, Teodoro
Frades-Payo, Belén
Ávila-Villanueva, Marina
Valentí-Soler, Meritxell
Benítez-Robredo, María T.
Bermejo-Aguña, Antonio
Pedrero-Pérez, Eduardo J.
Quilis-Sancho, Javier
Pastor, Ana B.
Fernández-Garrido, Concepción
Morales-Alonso, Sara
Diaz-Olalla, José M.
Santos, Nadine Correia
Maestú, Fernando
Gómez-Ramírez, Jaime
author_facet Fernández-Blázquez, Miguel A.
del Ser, Teodoro
Frades-Payo, Belén
Ávila-Villanueva, Marina
Valentí-Soler, Meritxell
Benítez-Robredo, María T.
Bermejo-Aguña, Antonio
Pedrero-Pérez, Eduardo J.
Quilis-Sancho, Javier
Pastor, Ana B.
Fernández-Garrido, Concepción
Morales-Alonso, Sara
Diaz-Olalla, José M.
Santos, Nadine Correia
Maestú, Fernando
Gómez-Ramírez, Jaime
author_sort Fernández-Blázquez, Miguel A.
collection PubMed
description The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represents an opportunity to explore which lifestyle factors are associated with healthy aging and which with the emergence of age-related diseases, especially Alzheimer’s type dementia. The project “Factors associated with healthy and pathologically aging in a sample of elderly people over 90 in the city of Madrid” (MADRID+90) brings together a multidisciplinary research team in neurodegenerative diseases that includes experts in epidemiology, neurology, neuropsychology, neuroimaging and computational neuroscience. In the first phase of the project, a stratified random sampling was carried out according to the census of the city of Madrid followed by a survey conducted on 191 people aged 90 and over. This survey gathered information on demographics, clinical data, lifestyles and cognitive status. Here, the main results of that survey are showed. The second phase of the project aims to characterize individual trajectories in the course of either healthy and pathological aging, from a group of 50 subjects over 90 who will undergo a comprehensive clinical examination comprised of neurological and cognitive testing, MRI and EEG. The ultimate goal of the project is to characterize the biophysical and clinical profiles of a population that tends to receive little attention in the literature. A better understanding of the rapidly increasing group of nonagenarians will also help to design new policies that minimize the impact and future social and economic consequences of rapidly aging societies.
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spelling pubmed-81282422021-05-27 MADRID+90 study on factors associated with longevity: Study design and preliminary data Fernández-Blázquez, Miguel A. del Ser, Teodoro Frades-Payo, Belén Ávila-Villanueva, Marina Valentí-Soler, Meritxell Benítez-Robredo, María T. Bermejo-Aguña, Antonio Pedrero-Pérez, Eduardo J. Quilis-Sancho, Javier Pastor, Ana B. Fernández-Garrido, Concepción Morales-Alonso, Sara Diaz-Olalla, José M. Santos, Nadine Correia Maestú, Fernando Gómez-Ramírez, Jaime PLoS One Research Article The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represents an opportunity to explore which lifestyle factors are associated with healthy aging and which with the emergence of age-related diseases, especially Alzheimer’s type dementia. The project “Factors associated with healthy and pathologically aging in a sample of elderly people over 90 in the city of Madrid” (MADRID+90) brings together a multidisciplinary research team in neurodegenerative diseases that includes experts in epidemiology, neurology, neuropsychology, neuroimaging and computational neuroscience. In the first phase of the project, a stratified random sampling was carried out according to the census of the city of Madrid followed by a survey conducted on 191 people aged 90 and over. This survey gathered information on demographics, clinical data, lifestyles and cognitive status. Here, the main results of that survey are showed. The second phase of the project aims to characterize individual trajectories in the course of either healthy and pathological aging, from a group of 50 subjects over 90 who will undergo a comprehensive clinical examination comprised of neurological and cognitive testing, MRI and EEG. The ultimate goal of the project is to characterize the biophysical and clinical profiles of a population that tends to receive little attention in the literature. A better understanding of the rapidly increasing group of nonagenarians will also help to design new policies that minimize the impact and future social and economic consequences of rapidly aging societies. Public Library of Science 2021-05-17 /pmc/articles/PMC8128242/ /pubmed/33999936 http://dx.doi.org/10.1371/journal.pone.0251796 Text en © 2021 Fernández-Blázquez et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fernández-Blázquez, Miguel A.
del Ser, Teodoro
Frades-Payo, Belén
Ávila-Villanueva, Marina
Valentí-Soler, Meritxell
Benítez-Robredo, María T.
Bermejo-Aguña, Antonio
Pedrero-Pérez, Eduardo J.
Quilis-Sancho, Javier
Pastor, Ana B.
Fernández-Garrido, Concepción
Morales-Alonso, Sara
Diaz-Olalla, José M.
Santos, Nadine Correia
Maestú, Fernando
Gómez-Ramírez, Jaime
MADRID+90 study on factors associated with longevity: Study design and preliminary data
title MADRID+90 study on factors associated with longevity: Study design and preliminary data
title_full MADRID+90 study on factors associated with longevity: Study design and preliminary data
title_fullStr MADRID+90 study on factors associated with longevity: Study design and preliminary data
title_full_unstemmed MADRID+90 study on factors associated with longevity: Study design and preliminary data
title_short MADRID+90 study on factors associated with longevity: Study design and preliminary data
title_sort madrid+90 study on factors associated with longevity: study design and preliminary data
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128242/
https://www.ncbi.nlm.nih.gov/pubmed/33999936
http://dx.doi.org/10.1371/journal.pone.0251796
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