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Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study

BACKGROUND: In patients with resectable colorectal liver metastases (CRLM), the role of pre- and postoperative systemic therapy continues to be debated. Previous studies have shown that circulating tumor DNA (ctDNA) analysis, as a marker of minimal residual disease, is a powerful prognostic factor i...

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Detalles Bibliográficos
Autores principales: Tie, Jeanne, Wang, Yuxuan, Cohen, Joshua, Li, Lu, Hong, Wei, Christie, Michael, Wong, Hui Li, Kosmider, Suzanne, Wong, Rachel, Thomson, Benjamin, Choi, Julian, Fox, Adrian, Field, Kathryn, Burge, Matthew, Shannon, Jenny, Kotasek, Dusan, Tebbutt, Niall C., Karapetis, Christos, Underhill, Craig, Haydon, Andrew, Schaeffer, Joy, Ptak, Janine, Tomasetti, Cristian, Papadopoulos, Nicholas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128260/
https://www.ncbi.nlm.nih.gov/pubmed/33939694
http://dx.doi.org/10.1371/journal.pmed.1003620