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LongAGE: defining breakpoints of genomic structural variants through optimal and memory efficient alignments of long reads
SUMMARY: Defining the precise location of structural variations (SVs) at single-nucleotide breakpoint resolution is a challenging problem due to large gaps in alignment. Previously, Alignment with Gap Excision (AGE) enabled us to define breakpoints of SVs at single-nucleotide resolution; however, AG...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128450/ https://www.ncbi.nlm.nih.gov/pubmed/32777815 http://dx.doi.org/10.1093/bioinformatics/btaa703 |