Cargando…

Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys

BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) is a key malaria prevention strategy in areas with moderate to high transmission. As part of the TIPTOP (Transforming IPT for Optimal Pregnancy) project, baseline information about IPTp coverage wa...

Descripción completa

Detalles Bibliográficos
Autores principales: Pons-Duran, Clara, Llach, Mireia, Sacoor, Charfudin, Sanz, Sergi, Macete, Eusebio, Arikpo, Iwara, Ramírez, Máximo, Meremikwu, Martin, Mbombo Ndombe, Didier, Méndez, Susana, Manun’Ebo, Manu F, Ramananjato, Ranto, Rabeza, Victor R, Tholandi, Maya, Roman, Elaine, Pagnoni, Franco, González, Raquel, Menéndez, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128463/
https://www.ncbi.nlm.nih.gov/pubmed/33349871
http://dx.doi.org/10.1093/ije/dyaa233
_version_ 1783694116461215744
author Pons-Duran, Clara
Llach, Mireia
Sacoor, Charfudin
Sanz, Sergi
Macete, Eusebio
Arikpo, Iwara
Ramírez, Máximo
Meremikwu, Martin
Mbombo Ndombe, Didier
Méndez, Susana
Manun’Ebo, Manu F
Ramananjato, Ranto
Rabeza, Victor R
Tholandi, Maya
Roman, Elaine
Pagnoni, Franco
González, Raquel
Menéndez, Clara
author_facet Pons-Duran, Clara
Llach, Mireia
Sacoor, Charfudin
Sanz, Sergi
Macete, Eusebio
Arikpo, Iwara
Ramírez, Máximo
Meremikwu, Martin
Mbombo Ndombe, Didier
Méndez, Susana
Manun’Ebo, Manu F
Ramananjato, Ranto
Rabeza, Victor R
Tholandi, Maya
Roman, Elaine
Pagnoni, Franco
González, Raquel
Menéndez, Clara
author_sort Pons-Duran, Clara
collection PubMed
description BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) is a key malaria prevention strategy in areas with moderate to high transmission. As part of the TIPTOP (Transforming IPT for Optimal Pregnancy) project, baseline information about IPTp coverage was collected in eight districts from four sub-Saharan countries: Democratic Republic of Congo (DRC), Madagascar, Mozambique and Nigeria. METHODS: Cross-sectional household surveys were conducted using a multistage cluster sampling design to estimate the coverage of IPTp and antenatal care attendance. Eligible participants were women of reproductive age who had ended a pregnancy in the 12 months preceding the interview and who had resided in the selected household during at least the past 4 months of pregnancy. Coverage was calculated using percentages and 95% confidence intervals. RESULTS: A total of 3911 women were interviewed from March to October 2018. Coverage of at least three doses of IPTp (IPTp3+) was 22% and 24% in DRC project districts; 23% and 12% in Madagascar districts; 11% and 16% in Nigeria local government areas; and 63% and 34% in Mozambique districts. In DRC, Madagascar and Nigeria, more than two-thirds of women attending at least four antenatal care visits during pregnancy received less than three doses of IPTp. CONCLUSIONS: The IPTp3+ uptake in the survey districts was far from the universal coverage. However, one of the study districts in Mozambique showed a much higher coverage of IPTp3+ than the other areas, which was also higher than the 2018 average national coverage of 41%. The reasons for the high IPTp3+ coverage in this Mozambican district are unclear and require further study.
format Online
Article
Text
id pubmed-8128463
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-81284632021-05-21 Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys Pons-Duran, Clara Llach, Mireia Sacoor, Charfudin Sanz, Sergi Macete, Eusebio Arikpo, Iwara Ramírez, Máximo Meremikwu, Martin Mbombo Ndombe, Didier Méndez, Susana Manun’Ebo, Manu F Ramananjato, Ranto Rabeza, Victor R Tholandi, Maya Roman, Elaine Pagnoni, Franco González, Raquel Menéndez, Clara Int J Epidemiol Other Infectious Diseases BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) is a key malaria prevention strategy in areas with moderate to high transmission. As part of the TIPTOP (Transforming IPT for Optimal Pregnancy) project, baseline information about IPTp coverage was collected in eight districts from four sub-Saharan countries: Democratic Republic of Congo (DRC), Madagascar, Mozambique and Nigeria. METHODS: Cross-sectional household surveys were conducted using a multistage cluster sampling design to estimate the coverage of IPTp and antenatal care attendance. Eligible participants were women of reproductive age who had ended a pregnancy in the 12 months preceding the interview and who had resided in the selected household during at least the past 4 months of pregnancy. Coverage was calculated using percentages and 95% confidence intervals. RESULTS: A total of 3911 women were interviewed from March to October 2018. Coverage of at least three doses of IPTp (IPTp3+) was 22% and 24% in DRC project districts; 23% and 12% in Madagascar districts; 11% and 16% in Nigeria local government areas; and 63% and 34% in Mozambique districts. In DRC, Madagascar and Nigeria, more than two-thirds of women attending at least four antenatal care visits during pregnancy received less than three doses of IPTp. CONCLUSIONS: The IPTp3+ uptake in the survey districts was far from the universal coverage. However, one of the study districts in Mozambique showed a much higher coverage of IPTp3+ than the other areas, which was also higher than the 2018 average national coverage of 41%. The reasons for the high IPTp3+ coverage in this Mozambican district are unclear and require further study. Oxford University Press 2020-12-08 /pmc/articles/PMC8128463/ /pubmed/33349871 http://dx.doi.org/10.1093/ije/dyaa233 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the International Epidemiological Association. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Other Infectious Diseases
Pons-Duran, Clara
Llach, Mireia
Sacoor, Charfudin
Sanz, Sergi
Macete, Eusebio
Arikpo, Iwara
Ramírez, Máximo
Meremikwu, Martin
Mbombo Ndombe, Didier
Méndez, Susana
Manun’Ebo, Manu F
Ramananjato, Ranto
Rabeza, Victor R
Tholandi, Maya
Roman, Elaine
Pagnoni, Franco
González, Raquel
Menéndez, Clara
Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys
title Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys
title_full Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys
title_fullStr Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys
title_full_unstemmed Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys
title_short Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys
title_sort coverage of intermittent preventive treatment of malaria in pregnancy in four sub-saharan countries: findings from household surveys
topic Other Infectious Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128463/
https://www.ncbi.nlm.nih.gov/pubmed/33349871
http://dx.doi.org/10.1093/ije/dyaa233
work_keys_str_mv AT ponsduranclara coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT llachmireia coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT sacoorcharfudin coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT sanzsergi coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT maceteeusebio coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT arikpoiwara coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT ramirezmaximo coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT meremikwumartin coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT mbombondombedidier coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT mendezsusana coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT manunebomanuf coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT ramananjatoranto coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT rabezavictorr coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT tholandimaya coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT romanelaine coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT pagnonifranco coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT gonzalezraquel coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys
AT menendezclara coverageofintermittentpreventivetreatmentofmalariainpregnancyinfoursubsaharancountriesfindingsfromhouseholdsurveys