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Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation

OBJECTIVE: The aim is to evaluate whether smart worklist prioritization by artificial intelligence (AI) can optimize the radiology workflow and reduce report turnaround times (RTATs) for critical findings in chest radiographs (CXRs). Furthermore, we investigate a method to counteract the effect of f...

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Autores principales: Baltruschat, Ivo, Steinmeister, Leonhard, Nickisch, Hannes, Saalbach, Axel, Grass, Michael, Adam, Gerhard, Knopp, Tobias, Ittrich, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128725/
https://www.ncbi.nlm.nih.gov/pubmed/33219850
http://dx.doi.org/10.1007/s00330-020-07480-7
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author Baltruschat, Ivo
Steinmeister, Leonhard
Nickisch, Hannes
Saalbach, Axel
Grass, Michael
Adam, Gerhard
Knopp, Tobias
Ittrich, Harald
author_facet Baltruschat, Ivo
Steinmeister, Leonhard
Nickisch, Hannes
Saalbach, Axel
Grass, Michael
Adam, Gerhard
Knopp, Tobias
Ittrich, Harald
author_sort Baltruschat, Ivo
collection PubMed
description OBJECTIVE: The aim is to evaluate whether smart worklist prioritization by artificial intelligence (AI) can optimize the radiology workflow and reduce report turnaround times (RTATs) for critical findings in chest radiographs (CXRs). Furthermore, we investigate a method to counteract the effect of false negative predictions by AI—resulting in an extremely and dangerously long RTAT, as CXRs are sorted to the end of the worklist. METHODS: We developed a simulation framework that models the current workflow at a university hospital by incorporating hospital-specific CXR generation rates and reporting rates and pathology distribution. Using this, we simulated the standard worklist processing “first-in, first-out” (FIFO) and compared it with a worklist prioritization based on urgency. Examination prioritization was performed by the AI, classifying eight different pathological findings ranked in descending order of urgency: pneumothorax, pleural effusion, infiltrate, congestion, atelectasis, cardiomegaly, mass, and foreign object. Furthermore, we introduced an upper limit for the maximum waiting time, after which the highest urgency is assigned to the examination. RESULTS: The average RTAT for all critical findings was significantly reduced in all prioritization simulations compared to the FIFO simulation (e.g., pneumothorax: 35.6 min vs. 80.1 min; p < 0.0001), while the maximum RTAT for most findings increased at the same time (e.g., pneumothorax: 1293 min vs 890 min; p < 0.0001). Our “upper limit” substantially reduced the maximum RTAT in all classes (e.g., pneumothorax: 979 min vs. 1293 min/1178 min; p < 0.0001). CONCLUSION: Our simulations demonstrate that smart worklist prioritization by AI can reduce the average RTAT for critical findings in CXRs while maintaining a small maximum RTAT as FIFO. KEY POINTS: • Development of a realistic clinical workflow simulator based on empirical data from a hospital allowed precise assessment of smart worklist prioritization using artificial intelligence. • Employing a smart worklist prioritization without a threshold for maximum waiting time runs the risk of false negative predictions of the artificial intelligence greatly increasing the report turnaround time. • Use of a state-of-the-art convolution neural network can reduce the average report turnaround time almost to the upper limit of a perfect classification algorithm (e.g., pneumothorax: 35.6 min vs. 30.4 min).
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spelling pubmed-81287252021-05-24 Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation Baltruschat, Ivo Steinmeister, Leonhard Nickisch, Hannes Saalbach, Axel Grass, Michael Adam, Gerhard Knopp, Tobias Ittrich, Harald Eur Radiol Imaging Informatics and Artificial Intelligence OBJECTIVE: The aim is to evaluate whether smart worklist prioritization by artificial intelligence (AI) can optimize the radiology workflow and reduce report turnaround times (RTATs) for critical findings in chest radiographs (CXRs). Furthermore, we investigate a method to counteract the effect of false negative predictions by AI—resulting in an extremely and dangerously long RTAT, as CXRs are sorted to the end of the worklist. METHODS: We developed a simulation framework that models the current workflow at a university hospital by incorporating hospital-specific CXR generation rates and reporting rates and pathology distribution. Using this, we simulated the standard worklist processing “first-in, first-out” (FIFO) and compared it with a worklist prioritization based on urgency. Examination prioritization was performed by the AI, classifying eight different pathological findings ranked in descending order of urgency: pneumothorax, pleural effusion, infiltrate, congestion, atelectasis, cardiomegaly, mass, and foreign object. Furthermore, we introduced an upper limit for the maximum waiting time, after which the highest urgency is assigned to the examination. RESULTS: The average RTAT for all critical findings was significantly reduced in all prioritization simulations compared to the FIFO simulation (e.g., pneumothorax: 35.6 min vs. 80.1 min; p < 0.0001), while the maximum RTAT for most findings increased at the same time (e.g., pneumothorax: 1293 min vs 890 min; p < 0.0001). Our “upper limit” substantially reduced the maximum RTAT in all classes (e.g., pneumothorax: 979 min vs. 1293 min/1178 min; p < 0.0001). CONCLUSION: Our simulations demonstrate that smart worklist prioritization by AI can reduce the average RTAT for critical findings in CXRs while maintaining a small maximum RTAT as FIFO. KEY POINTS: • Development of a realistic clinical workflow simulator based on empirical data from a hospital allowed precise assessment of smart worklist prioritization using artificial intelligence. • Employing a smart worklist prioritization without a threshold for maximum waiting time runs the risk of false negative predictions of the artificial intelligence greatly increasing the report turnaround time. • Use of a state-of-the-art convolution neural network can reduce the average report turnaround time almost to the upper limit of a perfect classification algorithm (e.g., pneumothorax: 35.6 min vs. 30.4 min). Springer Berlin Heidelberg 2020-11-21 2021 /pmc/articles/PMC8128725/ /pubmed/33219850 http://dx.doi.org/10.1007/s00330-020-07480-7 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Imaging Informatics and Artificial Intelligence
Baltruschat, Ivo
Steinmeister, Leonhard
Nickisch, Hannes
Saalbach, Axel
Grass, Michael
Adam, Gerhard
Knopp, Tobias
Ittrich, Harald
Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
title Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
title_full Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
title_fullStr Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
title_full_unstemmed Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
title_short Smart chest X-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
title_sort smart chest x-ray worklist prioritization using artificial intelligence: a clinical workflow simulation
topic Imaging Informatics and Artificial Intelligence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128725/
https://www.ncbi.nlm.nih.gov/pubmed/33219850
http://dx.doi.org/10.1007/s00330-020-07480-7
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