Alternative exon splicing and differential expression in pancreatic islets reveals candidate genes and pathways implicated in early diabetes development

Type 2 diabetes (T2D) has a strong genetic component. Most of the gene variants driving the pathogenesis of T2D seem to target pancreatic β-cell function. To identify novel gene variants acting at early stage of the disease, we analyzed whole transcriptome data to identify differential expression (D...

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Detalles Bibliográficos
Autores principales: Rehman, Sayeed ur, Schallschmidt, Tanja, Rasche, Axel, Knebel, Birgit, Stermann, Torben, Altenhofen, Delsi, Herwig, Ralf, Schürmann, Annette, Chadt, Alexandra, Al-Hasani, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128753/
https://www.ncbi.nlm.nih.gov/pubmed/33880624
http://dx.doi.org/10.1007/s00335-021-09869-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128753/
https://www.ncbi.nlm.nih.gov/pubmed/33880624
http://dx.doi.org/10.1007/s00335-021-09869-1

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