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Alternative exon splicing and differential expression in pancreatic islets reveals candidate genes and pathways implicated in early diabetes development
Type 2 diabetes (T2D) has a strong genetic component. Most of the gene variants driving the pathogenesis of T2D seem to target pancreatic β-cell function. To identify novel gene variants acting at early stage of the disease, we analyzed whole transcriptome data to identify differential expression (D...
Autores principales: | Rehman, Sayeed ur, Schallschmidt, Tanja, Rasche, Axel, Knebel, Birgit, Stermann, Torben, Altenhofen, Delsi, Herwig, Ralf, Schürmann, Annette, Chadt, Alexandra, Al-Hasani, Hadi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128753/ https://www.ncbi.nlm.nih.gov/pubmed/33880624 http://dx.doi.org/10.1007/s00335-021-09869-1 |
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