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Mutational analyses of novel rat models with targeted modifications in inflammatory bowel disease susceptibility genes
Mutations and single base pair polymorphisms in various genes have been associated with increased susceptibility to inflammatory bowel disease (IBD). We have created a series of rat strains carrying targeted genetic alterations within three IBD susceptibility genes: Nod2, Atg16l1, and Il23r, using C...
Autores principales: | Men, Hongsheng, Hankins, Miriam A., Bock, Anagha S., Beaton, Benjamin P., Davis, Daniel J., Chesney, Kari L., Bryda, Elizabeth C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128796/ https://www.ncbi.nlm.nih.gov/pubmed/33843019 http://dx.doi.org/10.1007/s00335-021-09868-2 |
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