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Mutational analyses of novel rat models with targeted modifications in inflammatory bowel disease susceptibility genes

Mutations and single base pair polymorphisms in various genes have been associated with increased susceptibility to inflammatory bowel disease (IBD). We have created a series of rat strains carrying targeted genetic alterations within three IBD susceptibility genes: Nod2, Atg16l1, and Il23r, using C...

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Detalles Bibliográficos
Autores principales: Men, Hongsheng, Hankins, Miriam A., Bock, Anagha S., Beaton, Benjamin P., Davis, Daniel J., Chesney, Kari L., Bryda, Elizabeth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128796/
https://www.ncbi.nlm.nih.gov/pubmed/33843019
http://dx.doi.org/10.1007/s00335-021-09868-2

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