Latent HIV-Exosomes Induce Mitochondrial Hyperfusion Due to Loss of Phosphorylated Dynamin-Related Protein 1 in Brain Endothelium

Damage to the cerebral vascular endothelium is a critical initiating event in the development of HIV-1-associated neurocognitive disorders. To study the role of mitochondria in cerebral endothelial dysfunction, we investigated how exosomes, isolated from both cell lines with integrated provirus and...

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Detalles Bibliográficos
Autores principales: Chandra, Partha K., Rutkai, Ibolya, Kim, Hogyoung, Braun, Stephen E., Abdel-Mageed, Asim B., Mondal, Debasis, Busija, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128843/
https://www.ncbi.nlm.nih.gov/pubmed/33586027
http://dx.doi.org/10.1007/s12035-021-02319-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128843/
https://www.ncbi.nlm.nih.gov/pubmed/33586027
http://dx.doi.org/10.1007/s12035-021-02319-8

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