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CADASIL from Bench to Bedside: Disease Models and Novel Therapeutic Approaches
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a monogenic disease caused by NOTCH3 mutations and characterized by typical clinical, neuroradiological, and pathological features. NOTCH3 belongs to a family of highly conserved transmembrane rec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128844/ https://www.ncbi.nlm.nih.gov/pubmed/33464533 http://dx.doi.org/10.1007/s12035-021-02282-4 |