ROS induces NETosis by oxidizing DNA and initiating DNA repair

Reactive oxygen species (ROS) are essential for neutrophil extracellular trap (NET) formation or NETosis. Nevertheless, how ROS induces NETosis is unknown. Neutrophil activation induces excess ROS production and a meaningless genome-wide transcription to facilitate chromatin decondensation. Here we...

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Detalles Bibliográficos
Autores principales: Azzouz, Dhia, Khan, Meraj A., Palaniyar, Nades
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128883/
https://www.ncbi.nlm.nih.gov/pubmed/34001856
http://dx.doi.org/10.1038/s41420-021-00491-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128883/
https://www.ncbi.nlm.nih.gov/pubmed/34001856
http://dx.doi.org/10.1038/s41420-021-00491-3

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