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Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice

The complement system plays a role in the formation of sub-retinal pigment epithelial (RPE) deposits in early stages of age-related macular degeneration (AMD). But the specific mechanisms that connect complement activation and deposit formation in AMD patients are unknown, which limits the developme...

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Detalles Bibliográficos
Autores principales:	Garland, Donita L., Pierce, Eric A., Fernandez-Godino, Rosario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128922/ https://www.ncbi.nlm.nih.gov/pubmed/34001980 http://dx.doi.org/10.1038/s41598-021-89978-8

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