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Rational Design of Peptide-Based Inhibitors Disrupting Protein-Protein Interactions
Protein-protein interactions (PPIs) are well-established as a class of promising drug targets for their implications in a wide range of biological processes. However, drug development toward PPIs is inevitably hampered by their flat and wide interfaces, which generally lack suitable pockets for liga...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128998/ https://www.ncbi.nlm.nih.gov/pubmed/34017824 http://dx.doi.org/10.3389/fchem.2021.682675 |