Cargando…
NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
Activation of non-shivering thermogenesis is considered a promising approach to lower body weight in obesity. p62 deficiency in adipocytes reduces systemic energy expenditure but its role in sustaining mitochondrial function and thermogenesis remains unresolved. NBR1 shares a remarkable structural s...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129077/ https://www.ncbi.nlm.nih.gov/pubmed/34001883 http://dx.doi.org/10.1038/s41467-021-23085-0 |