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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
Activation of non-shivering thermogenesis is considered a promising approach to lower body weight in obesity. p62 deficiency in adipocytes reduces systemic energy expenditure but its role in sustaining mitochondrial function and thermogenesis remains unresolved. NBR1 shares a remarkable structural s...
Autores principales: | Huang, Jianfeng, Linares, Juan F., Duran, Angeles, Xia, Wenmin, Saltiel, Alan R., Müller, Timo D., Diaz-Meco, Maria T., Moscat, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129077/ https://www.ncbi.nlm.nih.gov/pubmed/34001883 http://dx.doi.org/10.1038/s41467-021-23085-0 |
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