Outer membrane and phospholipid composition of the target membrane affect the antimicrobial potential of first- and second-generation lipophosphonoxins

Lipophosphonoxins (LPPOs) are small modular synthetic antibacterial compounds that target the cytoplasmic membrane. First-generation LPPOs (LPPO I) exhibit an antimicrobial activity against Gram-positive bacteria; however they do not exhibit any activity against Gram-negatives. Second-generation LPP...

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Detalles Bibliográficos
Autores principales: Látrová, Klára, Havlová, Noemi, Večeřová, Renata, Pinkas, Dominik, Bogdanová, Kateřina, Kolář, Milan, Fišer, Radovan, Konopásek, Ivo, Do Pham, Duy Dinh, Rejman, Dominik, Mikušová, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129119/
https://www.ncbi.nlm.nih.gov/pubmed/34001940
http://dx.doi.org/10.1038/s41598-021-89883-0

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