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Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129144/ https://www.ncbi.nlm.nih.gov/pubmed/34001941 http://dx.doi.org/10.1038/s41598-021-89602-9 |
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author | Guardiola, C. Márquez, A. Jiménez-Ramos, M. C. López, J. García Baratto-Roldán, A. Muñoz-Berbel, X. |
author_facet | Guardiola, C. Márquez, A. Jiménez-Ramos, M. C. López, J. García Baratto-Roldán, A. Muñoz-Berbel, X. |
author_sort | Guardiola, C. |
collection | PubMed |
description | This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications. |
format | Online Article Text |
id | pubmed-8129144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-81291442021-05-19 Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system Guardiola, C. Márquez, A. Jiménez-Ramos, M. C. López, J. García Baratto-Roldán, A. Muñoz-Berbel, X. Sci Rep Article This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications. Nature Publishing Group UK 2021-05-17 /pmc/articles/PMC8129144/ /pubmed/34001941 http://dx.doi.org/10.1038/s41598-021-89602-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Guardiola, C. Márquez, A. Jiménez-Ramos, M. C. López, J. García Baratto-Roldán, A. Muñoz-Berbel, X. Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
title | Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
title_full | Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
title_fullStr | Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
title_full_unstemmed | Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
title_short | Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
title_sort | dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129144/ https://www.ncbi.nlm.nih.gov/pubmed/34001941 http://dx.doi.org/10.1038/s41598-021-89602-9 |
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