Cargando…

Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system

This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic f...

Descripción completa

Detalles Bibliográficos
Autores principales: Guardiola, C., Márquez, A., Jiménez-Ramos, M. C., López, J. García, Baratto-Roldán, A., Muñoz-Berbel, X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129144/
https://www.ncbi.nlm.nih.gov/pubmed/34001941
http://dx.doi.org/10.1038/s41598-021-89602-9
_version_ 1783694256197599232
author Guardiola, C.
Márquez, A.
Jiménez-Ramos, M. C.
López, J. García
Baratto-Roldán, A.
Muñoz-Berbel, X.
author_facet Guardiola, C.
Márquez, A.
Jiménez-Ramos, M. C.
López, J. García
Baratto-Roldán, A.
Muñoz-Berbel, X.
author_sort Guardiola, C.
collection PubMed
description This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications.
format Online
Article
Text
id pubmed-8129144
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-81291442021-05-19 Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system Guardiola, C. Márquez, A. Jiménez-Ramos, M. C. López, J. García Baratto-Roldán, A. Muñoz-Berbel, X. Sci Rep Article This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications. Nature Publishing Group UK 2021-05-17 /pmc/articles/PMC8129144/ /pubmed/34001941 http://dx.doi.org/10.1038/s41598-021-89602-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Guardiola, C.
Márquez, A.
Jiménez-Ramos, M. C.
López, J. García
Baratto-Roldán, A.
Muñoz-Berbel, X.
Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_full Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_fullStr Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_full_unstemmed Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_short Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_sort dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129144/
https://www.ncbi.nlm.nih.gov/pubmed/34001941
http://dx.doi.org/10.1038/s41598-021-89602-9
work_keys_str_mv AT guardiolac dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem
AT marqueza dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem
AT jimenezramosmc dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem
AT lopezjgarcia dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem
AT barattoroldana dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem
AT munozberbelx dosimetrywithgafchromicfilmsbasedonanewmicrooptoelectromechanicalsystem