Cargando…

Xanthohumol Attenuated Inflammation and ECM Degradation by Mediating HO-1/C/EBPβ Pathway in Osteoarthritis Chondrocytes

Osteoarthritis (OA) is the most frequent and disabling disease in developed countries. The progressive degeneration of articular cartilage characterized as thinner and erosive. Inflammation is well-known to be involved in OA development. However, there are no effective therapeutic strategies to cure...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ming, Zhang, Rui, Zheng, Tiansheng, Chen, Zhixi, Ji, Guanglin, Peng, Fang, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129538/ https://www.ncbi.nlm.nih.gov/pubmed/34017261 http://dx.doi.org/10.3389/fphar.2021.680585

Ejemplares similares

Xanthohumol Inhibited Mechanical Stimulation-Induced Articular ECM Degradation by Mediating lncRNA GAS5/miR-27a Axis
por: Zheng, Tiansheng, et al.
Publicado: (2021)

Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice
por: Lin, Zeng, et al.
Publicado: (2019)

Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis
por: Ren, Chenghao, et al.
Publicado: (2021)

Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of TGF-β–Smad2/3 signaling of chondrocytes
por: Ge, Yanzhi, et al.
Publicado: (2023)

Scutellarin Attenuates the IL-1β-Induced Inflammation in Mouse Chondrocytes and Prevents Osteoarthritic Progression
por: Luo, Zucheng, et al.
Publicado: (2020)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
por: Yao, Minjun, et al.
Publicado: (2022)

Vindoline Attenuates Osteoarthritis Progression Through Suppressing the NF-κB and ERK Pathways in Both Chondrocytes and Subchondral Osteoclasts
por: Zhu, Meisong, et al.
Publicado: (2022)

Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis
por: Li, Yao, et al.
Publicado: (2019)

Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis
por: Sun, Weichao, et al.
Publicado: (2023)

ECM signals ECM degradation
por: Powell, Kendall
Publicado: (2006)

Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis
por: Pei, Wenbin, et al.
Publicado: (2021)

LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes
por: Lü, Guohua, et al.
Publicado: (2020)

Hesperetin Exhibits Anti-Inflammatory Effects on Chondrocytes via the AMPK Pathway to Attenuate Anterior Cruciate Ligament Transection-Induced Osteoarthritis
por: Wu, Jiaqin, et al.
Publicado: (2021)

Dihydroquercetin Activates AMPK/Nrf2/HO-1 Signaling in Macrophages and Attenuates Inflammation in LPS-Induced Endotoxemic Mice
por: Lei, Liming, et al.
Publicado: (2020)

Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats
por: Chu, Xiangyu, et al.
Publicado: (2020)

Psoralen downregulates osteoarthritis chondrocyte inflammation via an estrogen-like effect and attenuates osteoarthritis
por: Huang, Kui, et al.
Publicado: (2022)

Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo
por: Jiang, Zengxin, et al.
Publicado: (2022)

Vicenin 3 ameliorates ECM degradation by regulating the MAPK pathway in SW1353 chondrocytes
por: Chen, Yue-Yuan, et al.
Publicado: (2021)

Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway
por: Shao, Yuandong, et al.
Publicado: (2022)

Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes
por: Liang, Shuang, et al.
Publicado: (2018)

Anticancer Activity and Mechanism of Xanthohumol: A Prenylated Flavonoid From Hops (Humulus lupulus L.)
por: Jiang, Chuan-Hao, et al.
Publicado: (2018)

Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
por: Ma, Tianwen, et al.
Publicado: (2022)

Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model
por: Zhang, Lei, et al.
Publicado: (2017)

SPRY4 acts as an indicator of osteoarthritis severity and regulates chondrocyte hypertrophy and ECM protease expression
por: Park, Sunghyun, et al.
Publicado: (2021)

Correction for: Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats
por: Chu, Xiangyu, et al.
Publicado: (2022)

Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling
por: Paraiso, Ines L., et al.
Publicado: (2021)

Neutrophil Elastase Induces Chondrocyte Apoptosis and Facilitates the Occurrence of Osteoarthritis via Caspase Signaling Pathway
por: Wang, Ganyu, et al.
Publicado: (2021)

Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR
por: Huangfu, Yaru, et al.
Publicado: (2023)

Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
por: Guo, Zhou, et al.
Publicado: (2022)

The Attenuating Effect of Low-Intensity Pulsed Ultrasound on Hypoxia-Induced Rat Chondrocyte Damage in TMJ Osteoarthritis Based on TMT Labeling Quantitative Proteomic Analysis
por: Du, Sa, et al.
Publicado: (2021)

The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes
por: Gao, Yue, et al.
Publicado: (2014)

Synthesis of xanthohumol and xanthohumol-d(3) from naringenin
por: Andrusiak, Joanna, et al.
Publicado: (2021)

XMU-MP-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis
por: Hao, Xue, et al.
Publicado: (2022)

Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes
por: Tu, Chang, et al.
Publicado: (2019)

Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development
por: Zhou, Haikang, et al.
Publicado: (2021)

Sirt6 attenuates chondrocyte senescence and osteoarthritis progression
por: Ji, Ming-liang, et al.
Publicado: (2022)

Corrigendum: Deferoxamine alleviates osteoarthritis by inhibiting chondrocyte ferroptosis and activating the Nrf2 pathway
por: Guo, Zhou, et al.
Publicado: (2023)

Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway
por: Ma, Tianwen, et al.
Publicado: (2022)

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
por: Liu, Zhuanghua, et al.
Publicado: (2022)

ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways
por: Kundu, Payel, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ju58mro0b7mntvq2hsmntobqat