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Pharmacokinetics and Pharmacodynamics of Nemonoxacin in a Neutropenic Murine Lung Infection Model Against Streptococcus Pneumoniae

Nemonoxacin, a novel nonfluorinated quinolone for the treatment of community-acquired pneumonia. We reported the pharmacokinetic/pharmacodynamic (PK/PD) targets and PK/PD breakpoints of nemonoxacin against Streptococcus pneumoniae using a neutropenic murine lung infection model. Single-dose PK analy...

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Detalles Bibliográficos
Autores principales:	Li, Xin, Chen, Yuancheng, Xu, Xiaoyong, Li, Yi, Fan, Yaxin, Liu, Xiaofen, Bian, Xingchen, Wu, Hailan, Zhao, Xu, Feng, Meiqing, Guo, Beining, Zhang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129567/ https://www.ncbi.nlm.nih.gov/pubmed/34017256 http://dx.doi.org/10.3389/fphar.2021.658558

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