Continuous MYD88 Activation Is Associated With Expansion and Then Transformation of IgM Differentiating Plasma Cells

Activating mutations of MYD88 (MYD88(L265P) being the far most frequent) are found in most cases of Waldenström macroglobulinemia (WM) as well as in various aggressive B-cell lymphoma entities with features of plasma cell (PC) differentiation, such as activated B-cell type diffuse large B-cell lymph...

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Detalles Bibliográficos
Autores principales: Ouk, Catherine, Roland, Lilian, Gachard, Nathalie, Poulain, Stéphanie, Oblet, Christelle, Rizzo, David, Saintamand, Alexis, Lemasson, Quentin, Carrion, Claire, Thomas, Morgane, Balabanian, Karl, Espéli, Marion, Parrens, Marie, Soubeyran, Isabelle, Boulin, Mélanie, Faumont, Nathalie, Feuillard, Jean, Vincent-Fabert, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129569/
https://www.ncbi.nlm.nih.gov/pubmed/34017329
http://dx.doi.org/10.3389/fimmu.2021.641692

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