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PD-1-inhibitor pembrolizumab for treatment of progressive multifocal leukoencephalopathy
The reactivation of human JC polyoma virus (JCPyV) results in lytic infection of oligodendrocytes and neuronal cells. The corresponding clinical picture is called progressive multifocal leukoencephalopathy (PML) and results mostly from a disease-related or drug-induced immunosuppression. The opportu...
Autores principales: | Möhn, Nora, Wattjes, Mike P., Adams, Ortwin, Nay, Sandra, Tkachenko, Daria, Salge, Friederike, Heine, Johanne, Pars, Kaweh, Höglinger, Günter, Respondek, Gesine, Stangel, Martin, Skripuletz, Thomas, Jacobs, Roland, Sühs, Kurt-Wolfram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129640/ https://www.ncbi.nlm.nih.gov/pubmed/34035834 http://dx.doi.org/10.1177/1756286421993684 |
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