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Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients

Background: Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the...

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Autores principales: Ferinauli, Ferinauli, Narulita, Sari, Hijriyati, Yoanita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129748/
https://www.ncbi.nlm.nih.gov/pubmed/33855401
http://dx.doi.org/10.4081/jphr.2021.2184
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author Ferinauli, Ferinauli
Narulita, Sari
Hijriyati, Yoanita
author_facet Ferinauli, Ferinauli
Narulita, Sari
Hijriyati, Yoanita
author_sort Ferinauli, Ferinauli
collection PubMed
description Background: Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the use of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients. Design and Methods: This study used a descriptive design with 53 respondents. Data were analyzed using the contingency coefficient correlation and Spearman Rank test methods. Results: The results of the first study showed no positive effect between the use of antipsychotics on orthostatic hypotension in schizophrenic patients. In addition, a contingency coefficient correlation (C) of 0.199 and p-value of 0.335 (p>0.05) was obtained. The results of the second study showed that there was a significant positive effect between orthostatic hypotension on the risk of falling in schizophrenic patients with a value of r = 0.483 and a pvalue of 0.000 (p0.001). Conclusion: It was suggested that the development of this study’s result is needed for further research in dealing with the incidence of orthostatic hypotension in order to prevent or reduce the risk of falling in schizophrenic patients.
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spelling pubmed-81297482021-05-24 Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients Ferinauli, Ferinauli Narulita, Sari Hijriyati, Yoanita J Public Health Res Article Background: Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the use of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients. Design and Methods: This study used a descriptive design with 53 respondents. Data were analyzed using the contingency coefficient correlation and Spearman Rank test methods. Results: The results of the first study showed no positive effect between the use of antipsychotics on orthostatic hypotension in schizophrenic patients. In addition, a contingency coefficient correlation (C) of 0.199 and p-value of 0.335 (p>0.05) was obtained. The results of the second study showed that there was a significant positive effect between orthostatic hypotension on the risk of falling in schizophrenic patients with a value of r = 0.483 and a pvalue of 0.000 (p0.001). Conclusion: It was suggested that the development of this study’s result is needed for further research in dealing with the incidence of orthostatic hypotension in order to prevent or reduce the risk of falling in schizophrenic patients. PAGEPress Publications, Pavia, Italy 2021-04-14 /pmc/articles/PMC8129748/ /pubmed/33855401 http://dx.doi.org/10.4081/jphr.2021.2184 Text en ©Copyright: the Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Ferinauli, Ferinauli
Narulita, Sari
Hijriyati, Yoanita
Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
title Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
title_full Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
title_fullStr Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
title_full_unstemmed Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
title_short Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
title_sort effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129748/
https://www.ncbi.nlm.nih.gov/pubmed/33855401
http://dx.doi.org/10.4081/jphr.2021.2184
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