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Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients
Background: Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129748/ https://www.ncbi.nlm.nih.gov/pubmed/33855401 http://dx.doi.org/10.4081/jphr.2021.2184 |
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author | Ferinauli, Ferinauli Narulita, Sari Hijriyati, Yoanita |
author_facet | Ferinauli, Ferinauli Narulita, Sari Hijriyati, Yoanita |
author_sort | Ferinauli, Ferinauli |
collection | PubMed |
description | Background: Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the use of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients. Design and Methods: This study used a descriptive design with 53 respondents. Data were analyzed using the contingency coefficient correlation and Spearman Rank test methods. Results: The results of the first study showed no positive effect between the use of antipsychotics on orthostatic hypotension in schizophrenic patients. In addition, a contingency coefficient correlation (C) of 0.199 and p-value of 0.335 (p>0.05) was obtained. The results of the second study showed that there was a significant positive effect between orthostatic hypotension on the risk of falling in schizophrenic patients with a value of r = 0.483 and a pvalue of 0.000 (p0.001). Conclusion: It was suggested that the development of this study’s result is needed for further research in dealing with the incidence of orthostatic hypotension in order to prevent or reduce the risk of falling in schizophrenic patients. |
format | Online Article Text |
id | pubmed-8129748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-81297482021-05-24 Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients Ferinauli, Ferinauli Narulita, Sari Hijriyati, Yoanita J Public Health Res Article Background: Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the use of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients. Design and Methods: This study used a descriptive design with 53 respondents. Data were analyzed using the contingency coefficient correlation and Spearman Rank test methods. Results: The results of the first study showed no positive effect between the use of antipsychotics on orthostatic hypotension in schizophrenic patients. In addition, a contingency coefficient correlation (C) of 0.199 and p-value of 0.335 (p>0.05) was obtained. The results of the second study showed that there was a significant positive effect between orthostatic hypotension on the risk of falling in schizophrenic patients with a value of r = 0.483 and a pvalue of 0.000 (p0.001). Conclusion: It was suggested that the development of this study’s result is needed for further research in dealing with the incidence of orthostatic hypotension in order to prevent or reduce the risk of falling in schizophrenic patients. PAGEPress Publications, Pavia, Italy 2021-04-14 /pmc/articles/PMC8129748/ /pubmed/33855401 http://dx.doi.org/10.4081/jphr.2021.2184 Text en ©Copyright: the Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Ferinauli, Ferinauli Narulita, Sari Hijriyati, Yoanita Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
title | Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
title_full | Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
title_fullStr | Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
title_full_unstemmed | Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
title_short | Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
title_sort | effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129748/ https://www.ncbi.nlm.nih.gov/pubmed/33855401 http://dx.doi.org/10.4081/jphr.2021.2184 |
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