Rab40–Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration

Rab40b is a SOCS box–containing protein that regulates the secretion of MMPs to facilitate extracellular matrix remodeling during cell migration. Here, we show that Rab40b interacts with Cullin5 via the Rab40b SOCS domain. We demonstrate that loss of Rab40b–Cullin5 binding decreases cell motility an...

Descripción completa

Detalles Bibliográficos
Autores principales: Linklater, Erik S., Duncan, Emily D., Han, Ke-Jun, Kaupinis, Algirdas, Valius, Mindaugas, Lyons, Traci R., Prekeris, Rytis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129794/
https://www.ncbi.nlm.nih.gov/pubmed/33999101
http://dx.doi.org/10.1083/jcb.202008060

Ejemplares similares

Ejemplares similares