Synapses have autophagy under control

Regulation of autophagy in neurons remains unclear. In this issue, Kulkarni et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202002084) show with elegant live imaging that in dendrites, but not in axons, autophagosome motility and function is regulated by synaptic activity.

Detalles Bibliográficos
Autor principal: Guimas Almeida, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129805/
https://www.ncbi.nlm.nih.gov/pubmed/33988696
http://dx.doi.org/10.1083/jcb.202105008
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author Guimas Almeida, Claudia
author_facet Guimas Almeida, Claudia
author_sort Guimas Almeida, Claudia
collection PubMed
description Regulation of autophagy in neurons remains unclear. In this issue, Kulkarni et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202002084) show with elegant live imaging that in dendrites, but not in axons, autophagosome motility and function is regulated by synaptic activity.
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spelling pubmed-81298052021-12-07 Synapses have autophagy under control Guimas Almeida, Claudia J Cell Biol Spotlight Regulation of autophagy in neurons remains unclear. In this issue, Kulkarni et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202002084) show with elegant live imaging that in dendrites, but not in axons, autophagosome motility and function is regulated by synaptic activity. Rockefeller University Press 2021-05-14 /pmc/articles/PMC8129805/ /pubmed/33988696 http://dx.doi.org/10.1083/jcb.202105008 Text en © 2021 Guimas Almeida http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Guimas Almeida, Claudia
Synapses have autophagy under control
title Synapses have autophagy under control
title_full Synapses have autophagy under control
title_fullStr Synapses have autophagy under control
title_full_unstemmed Synapses have autophagy under control
title_short Synapses have autophagy under control
title_sort synapses have autophagy under control
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129805/
https://www.ncbi.nlm.nih.gov/pubmed/33988696
http://dx.doi.org/10.1083/jcb.202105008
work_keys_str_mv AT guimasalmeidaclaudia synapseshaveautophagyundercontrol

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