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A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil

BACKGROUND: Our goal was to identify genetic risk factors for cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. METHODS: Genotyping 2066 CL cases and 2046 controls using Illumina HumanCoreExomeBeadChips provided data for 4 498 586 imputed single-nucleotide variants (SNVs). A genome-wid...

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Detalles Bibliográficos
Autores principales: Castellucci, Léa C, Almeida, Lucas, Cherlin, Svetlana, Fakiola, Michaela, Francis, Richard W, Carvalho, Edgar M, Santos da Hora, Anadílton, do Lago, Tainã Souza, Figueiredo, Amanda B, Cavalcanti, Clara M, Alves, Natalia S, Morais, Katia L P, Teixeira-Carvalho, Andréa, Dutra, Walderez O, Gollob, Kenneth J, Cordell, Heather J, Blackwell, Jenefer M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130031/
https://www.ncbi.nlm.nih.gov/pubmed/32830257
http://dx.doi.org/10.1093/cid/ciaa1230

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