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A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil
BACKGROUND: Our goal was to identify genetic risk factors for cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. METHODS: Genotyping 2066 CL cases and 2046 controls using Illumina HumanCoreExomeBeadChips provided data for 4 498 586 imputed single-nucleotide variants (SNVs). A genome-wid...
Autores principales: | Castellucci, Léa C, Almeida, Lucas, Cherlin, Svetlana, Fakiola, Michaela, Francis, Richard W, Carvalho, Edgar M, Santos da Hora, Anadílton, do Lago, Tainã Souza, Figueiredo, Amanda B, Cavalcanti, Clara M, Alves, Natalia S, Morais, Katia L P, Teixeira-Carvalho, Andréa, Dutra, Walderez O, Gollob, Kenneth J, Cordell, Heather J, Blackwell, Jenefer M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130031/ https://www.ncbi.nlm.nih.gov/pubmed/32830257 http://dx.doi.org/10.1093/cid/ciaa1230 |
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