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Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report
BACKGROUND: Pheochromocytoma is a rare endocrine tumor arising from chromaffin cells and having extensive and profound effects on the cardiovascular system by continuously or intermittently releasing catecholamines. The clinical manifestations of pheochromocytoma are diverse, and the typical triad,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130096/ https://www.ncbi.nlm.nih.gov/pubmed/34046479 http://dx.doi.org/10.12998/wjcc.v9.i15.3752 |
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author | Wu, Hao-Yu Cao, Yi-Wei Gao, Tian-Jiao Fu, Jian-Li Liang, Lei |
author_facet | Wu, Hao-Yu Cao, Yi-Wei Gao, Tian-Jiao Fu, Jian-Li Liang, Lei |
author_sort | Wu, Hao-Yu |
collection | PubMed |
description | BACKGROUND: Pheochromocytoma is a rare endocrine tumor arising from chromaffin cells and having extensive and profound effects on the cardiovascular system by continuously or intermittently releasing catecholamines. The clinical manifestations of pheochromocytoma are diverse, and the typical triad, including episodic headache, palpitations, and sweating, only occurs in 24% of pheochromocytoma patients, which often misleads clinicians into making an incorrect diagnosis. We herein report the case of a patient with intermittent chest pain and elevated myocardial enzymes for 2 years who was diagnosed with pheochromocytoma. CASE SUMMARY: A 49-year-old woman presented with intermittent chest pain for 2 years. Two years ago, the patient experienced chest pain and was diagnosed with acute myocardial infarction, with 25% stenosis in the left circumflex. The patient still had intermittent chest pain after discharge. Two hours before admission to our hospital, the patient experienced chest pain with nausea and vomiting, lasting for 20 min. Troponin I and urinary norepinephrine and catecholamine levels were elevated. An electrocardiogram indicated QT prolongation and ST-segment depression in leads II, III, aVF, and V3-V6. A coronary computed tomography angiogram revealed no evidence of coronary artery disease. Echocardiography showed left ventricular enlargement and a decreased posterior inferior wall motion amplitude. Contrast-enhanced computed tomography demonstrated an inhomogeneous right adrenal mass. The patient successfully underwent laparoscopic right adrenalectomy, and histopathology confirmed adrenal pheochromocytoma. During the first-year follow-up visits, the patient was asymptomatic. The abnormal changes on echocardiography and electrocardiogram disappeared. CONCLUSION: Clinicians should be aware of pheochromocytoma. A timely and accurate diagnosis of pheochromocytoma is essential for alleviating serious cardiac complications. |
format | Online Article Text |
id | pubmed-8130096 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-81300962021-05-26 Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report Wu, Hao-Yu Cao, Yi-Wei Gao, Tian-Jiao Fu, Jian-Li Liang, Lei World J Clin Cases Case Report BACKGROUND: Pheochromocytoma is a rare endocrine tumor arising from chromaffin cells and having extensive and profound effects on the cardiovascular system by continuously or intermittently releasing catecholamines. The clinical manifestations of pheochromocytoma are diverse, and the typical triad, including episodic headache, palpitations, and sweating, only occurs in 24% of pheochromocytoma patients, which often misleads clinicians into making an incorrect diagnosis. We herein report the case of a patient with intermittent chest pain and elevated myocardial enzymes for 2 years who was diagnosed with pheochromocytoma. CASE SUMMARY: A 49-year-old woman presented with intermittent chest pain for 2 years. Two years ago, the patient experienced chest pain and was diagnosed with acute myocardial infarction, with 25% stenosis in the left circumflex. The patient still had intermittent chest pain after discharge. Two hours before admission to our hospital, the patient experienced chest pain with nausea and vomiting, lasting for 20 min. Troponin I and urinary norepinephrine and catecholamine levels were elevated. An electrocardiogram indicated QT prolongation and ST-segment depression in leads II, III, aVF, and V3-V6. A coronary computed tomography angiogram revealed no evidence of coronary artery disease. Echocardiography showed left ventricular enlargement and a decreased posterior inferior wall motion amplitude. Contrast-enhanced computed tomography demonstrated an inhomogeneous right adrenal mass. The patient successfully underwent laparoscopic right adrenalectomy, and histopathology confirmed adrenal pheochromocytoma. During the first-year follow-up visits, the patient was asymptomatic. The abnormal changes on echocardiography and electrocardiogram disappeared. CONCLUSION: Clinicians should be aware of pheochromocytoma. A timely and accurate diagnosis of pheochromocytoma is essential for alleviating serious cardiac complications. Baishideng Publishing Group Inc 2021-05-26 2021-05-26 /pmc/articles/PMC8130096/ /pubmed/34046479 http://dx.doi.org/10.12998/wjcc.v9.i15.3752 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Wu, Hao-Yu Cao, Yi-Wei Gao, Tian-Jiao Fu, Jian-Li Liang, Lei Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report |
title | Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report |
title_full | Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report |
title_fullStr | Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report |
title_full_unstemmed | Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report |
title_short | Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report |
title_sort | pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130096/ https://www.ncbi.nlm.nih.gov/pubmed/34046479 http://dx.doi.org/10.12998/wjcc.v9.i15.3752 |
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