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An improved DNA-binding hot spot residues prediction method by exploring interfacial neighbor properties

BACKGROUND: DNA-binding hot spots are dominant and fundamental residues that contribute most of the binding free energy yet accounting for a small portion of protein–DNA interfaces. As experimental methods for identifying hot spots are time-consuming and costly, high-efficiency computational approac...

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Detalles Bibliográficos
Autores principales:	Zhang, Sijia, Wang, Lihua, Zhao, Le, Li, Menglu, Liu, Mengya, Li, Ke, Bin, Yannan, Xia, Junfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130120/ https://www.ncbi.nlm.nih.gov/pubmed/34000983 http://dx.doi.org/10.1186/s12859-020-03871-1

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