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Bone marrow mesenchymal stem cells promote prostate cancer cell stemness via cell–cell contact to activate the Jagged1/Notch1 pathway

BACKGROUND: Mesenchymal stem cells (MSCs) play a crucial role in cancer development and tumor resistance to therapy in prostate cancer, but the influence of MSCs on the stemness potential of PCa cells by cell–cell contact remains unclear. In this study, we investigated the effect of direct contact o...

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Detalles Bibliográficos
Autores principales:	Cheng, Ji-wen, Duan, Li-xia, Yu, Yang, Wang, Pu, Feng, Jia-le, Feng, Guan-zheng, Liu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130143/ https://www.ncbi.nlm.nih.gov/pubmed/34001269 http://dx.doi.org/10.1186/s13578-021-00599-0

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