Cargando…

MMP-2 is a novel histone H3 N-terminal protease necessary for myogenic gene activation

BACKGROUND: Selective proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during eukaryotic development, generating a cleaved histone H3 (H3cl) product within a small, but significant, portion of the genome. Although increasing evidence supports a regulatory role for H3NT pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Rice, Judd C., Weekley, Benjamin H., Kanholm, Tomas, Chen, Zhihui, Lee, Sunyoung, Fernandez, Daniel J., Abrahamson, Rachel, Castaldi, Alessandra, Borok, Zea, Dynlacht, Brian D., An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130154/
https://www.ncbi.nlm.nih.gov/pubmed/34001241
http://dx.doi.org/10.1186/s13072-021-00398-4

Ejemplares similares