Violet-light suppression of thermogenesis by Opsin 5 hypothalamic neurons

The opsin family of G-protein coupled receptors are employed as light detectors in animals. Opsin 5 (neuropsin, OPN5) is a highly conserved, violet light (380 nm λ(max)) sensitive opsin(1,2). In mice, OPN5 is a known photoreceptor in retina(3) and skin(4) but is also expressed in the hypothalamic pr...

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Detalles Bibliográficos
Autores principales: Zhang, Kevin X., D’Souza, Shane, Upton, Brian A., Kernodle, Stace, Vemaraju, Shruti, Nayak, Gowri, Gaitonde, Kevin D., Holt, Amanda L., Linne, Courtney D., Smith, April N., Petts, Nathan T., Batie, Matthew, Mukherjee, Rajib, Tiwari, Durgesh, Buhr, Ethan D., Van Gelder, Russell N., Gross, Christina, Sweeney, Alison, Sanchez-Gurmaches, Joan, Seeley, Randy J., Lang, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130195/
https://www.ncbi.nlm.nih.gov/pubmed/32879486
http://dx.doi.org/10.1038/s41586-020-2683-0

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