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Male Triple-Negative Breast Cancer

Male breast cancer is a rarely encountered disease, when compared with female breast cancer, often detected in more advanced stage at the time of diagnosis, and associated with more lymph node metastasis rates, more estrogen receptors positivity, and less human epidermal growth factor receptor-2 exp...

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Autores principales: Qavi, Qasif, Alkistawi, Firas, Kumar, Shashi, Ahmed, Rizwan, Saad Abdalla Al-Zawi, Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130197/
https://www.ncbi.nlm.nih.gov/pubmed/34017657
http://dx.doi.org/10.7759/cureus.14542
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author Qavi, Qasif
Alkistawi, Firas
Kumar, Shashi
Ahmed, Rizwan
Saad Abdalla Al-Zawi, Abdalla
author_facet Qavi, Qasif
Alkistawi, Firas
Kumar, Shashi
Ahmed, Rizwan
Saad Abdalla Al-Zawi, Abdalla
author_sort Qavi, Qasif
collection PubMed
description Male breast cancer is a rarely encountered disease, when compared with female breast cancer, often detected in more advanced stage at the time of diagnosis, and associated with more lymph node metastasis rates, more estrogen receptors positivity, and less human epidermal growth factor receptor-2 expression (HER-2) rates. Surgical management also shows some difference, where the most common operative technique of male breast cancer patients is mastectomy and/or axillary surgery. Triple-negative breast cancer is less frequent than other subtypes and is associated with poorer prognosis. This is because of its association with higher histopathological grade than that in other types of breast cancer. Only fewer treatment options are available compared to hormone-positive, HER-2 positive breast cancer. We are present a case of 71-year-old gentleman with triple-negative breast cancer.
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spelling pubmed-81301972021-05-19 Male Triple-Negative Breast Cancer Qavi, Qasif Alkistawi, Firas Kumar, Shashi Ahmed, Rizwan Saad Abdalla Al-Zawi, Abdalla Cureus Genetics Male breast cancer is a rarely encountered disease, when compared with female breast cancer, often detected in more advanced stage at the time of diagnosis, and associated with more lymph node metastasis rates, more estrogen receptors positivity, and less human epidermal growth factor receptor-2 expression (HER-2) rates. Surgical management also shows some difference, where the most common operative technique of male breast cancer patients is mastectomy and/or axillary surgery. Triple-negative breast cancer is less frequent than other subtypes and is associated with poorer prognosis. This is because of its association with higher histopathological grade than that in other types of breast cancer. Only fewer treatment options are available compared to hormone-positive, HER-2 positive breast cancer. We are present a case of 71-year-old gentleman with triple-negative breast cancer. Cureus 2021-04-18 /pmc/articles/PMC8130197/ /pubmed/34017657 http://dx.doi.org/10.7759/cureus.14542 Text en Copyright © 2021, Qavi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Genetics
Qavi, Qasif
Alkistawi, Firas
Kumar, Shashi
Ahmed, Rizwan
Saad Abdalla Al-Zawi, Abdalla
Male Triple-Negative Breast Cancer
title Male Triple-Negative Breast Cancer
title_full Male Triple-Negative Breast Cancer
title_fullStr Male Triple-Negative Breast Cancer
title_full_unstemmed Male Triple-Negative Breast Cancer
title_short Male Triple-Negative Breast Cancer
title_sort male triple-negative breast cancer
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130197/
https://www.ncbi.nlm.nih.gov/pubmed/34017657
http://dx.doi.org/10.7759/cureus.14542
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