Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster

OBJECTIVE: Amaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H...

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Detalles Bibliográficos
Autores principales: Johnmark, Ndinawe, Kinyi, Hellen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130338/
https://www.ncbi.nlm.nih.gov/pubmed/34001252
http://dx.doi.org/10.1186/s13104-021-05603-x
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author Johnmark, Ndinawe
Kinyi, Hellen W.
author_facet Johnmark, Ndinawe
Kinyi, Hellen W.
author_sort Johnmark, Ndinawe
collection PubMed
description OBJECTIVE: Amaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H(2)O(2) induced oxidative stress in Drosophila melanogaster flies was assessed. RESULTS: Consumption of Amaranth leaf extract was associated with increased survival on exposure to H(2)o(2) in a dose dependent manner in Drosophila melanogaster flies. The study concludes that the ethanolic extract of Amaranth leaves offer protection against hydrogen peroxide-induced oxidative stress. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-021-05603-x.
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spelling pubmed-81303382021-05-18 Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster Johnmark, Ndinawe Kinyi, Hellen W. BMC Res Notes Research Note OBJECTIVE: Amaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H(2)O(2) induced oxidative stress in Drosophila melanogaster flies was assessed. RESULTS: Consumption of Amaranth leaf extract was associated with increased survival on exposure to H(2)o(2) in a dose dependent manner in Drosophila melanogaster flies. The study concludes that the ethanolic extract of Amaranth leaves offer protection against hydrogen peroxide-induced oxidative stress. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-021-05603-x. BioMed Central 2021-05-17 /pmc/articles/PMC8130338/ /pubmed/34001252 http://dx.doi.org/10.1186/s13104-021-05603-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Johnmark, Ndinawe
Kinyi, Hellen W.
Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
title Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
title_full Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
title_fullStr Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
title_full_unstemmed Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
title_short Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
title_sort amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in drosophila melanogaster
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130338/
https://www.ncbi.nlm.nih.gov/pubmed/34001252
http://dx.doi.org/10.1186/s13104-021-05603-x
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