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Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data

BACKGROUND: Quality of life and patient self-determination are key elements in successful palliative care. To achieve these goals, a robust prediction of the remaining survival time is useful as it can provide patients and their relatives with information for individual goal setting including approp...

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Autores principales: Just, Johannes, Schmitz, Marie-Therese, Grabenhorst, Ulrich, Joist, Thomas, Horn, Kirsten, Engel, Bettina, Weckbecker, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130350/
https://www.ncbi.nlm.nih.gov/pubmed/34001099
http://dx.doi.org/10.1186/s12904-021-00762-x
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author Just, Johannes
Schmitz, Marie-Therese
Grabenhorst, Ulrich
Joist, Thomas
Horn, Kirsten
Engel, Bettina
Weckbecker, Klaus
author_facet Just, Johannes
Schmitz, Marie-Therese
Grabenhorst, Ulrich
Joist, Thomas
Horn, Kirsten
Engel, Bettina
Weckbecker, Klaus
author_sort Just, Johannes
collection PubMed
description BACKGROUND: Quality of life and patient self-determination are key elements in successful palliative care. To achieve these goals, a robust prediction of the remaining survival time is useful as it can provide patients and their relatives with information for individual goal setting including appropriate priorities. The Aim of our study was to assess factors that influence survival after enrollment into ambulatory palliative care. METHODS: In this cross-sectional, multicenter study (n = 14 study centers) clinical records of all palliative care patients who were treated in 2017 were extracted and underwent statistical analysis. The main outcome criterion was the association of survival time with clinical characteristics such as age, type of disease, symptoms and performance status. RESULTS: A total of 6282 cases were evaluated. Median time of survival was 26 days (95 % CI: 25–27 days). The strongest association for an increased hazard ratio was found for the following characteristics: moderate/severe weakness (aHR: 1.91; 95 % CI: 1.27–2.86) Karnofsky score 10–30 (aHR: 1.80; 95 % CI: 1.67–1.95), and age > 85 (aHR: 1.50; 95 % CI: 1.37–1.64). Surprisingly, type of disease (cancer vs. non-cancer) was not associated with a change in survival time (aHR: 1.03; 95 % CI: 0.96–1.10). CONCLUSIONS: In this cross-sectional study, the most relevant predictor for a short survival time in specialized ambulatory palliative care was the performance status while type of disease was irrelevant to survival.
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spelling pubmed-81303502021-05-18 Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data Just, Johannes Schmitz, Marie-Therese Grabenhorst, Ulrich Joist, Thomas Horn, Kirsten Engel, Bettina Weckbecker, Klaus BMC Palliat Care Research BACKGROUND: Quality of life and patient self-determination are key elements in successful palliative care. To achieve these goals, a robust prediction of the remaining survival time is useful as it can provide patients and their relatives with information for individual goal setting including appropriate priorities. The Aim of our study was to assess factors that influence survival after enrollment into ambulatory palliative care. METHODS: In this cross-sectional, multicenter study (n = 14 study centers) clinical records of all palliative care patients who were treated in 2017 were extracted and underwent statistical analysis. The main outcome criterion was the association of survival time with clinical characteristics such as age, type of disease, symptoms and performance status. RESULTS: A total of 6282 cases were evaluated. Median time of survival was 26 days (95 % CI: 25–27 days). The strongest association for an increased hazard ratio was found for the following characteristics: moderate/severe weakness (aHR: 1.91; 95 % CI: 1.27–2.86) Karnofsky score 10–30 (aHR: 1.80; 95 % CI: 1.67–1.95), and age > 85 (aHR: 1.50; 95 % CI: 1.37–1.64). Surprisingly, type of disease (cancer vs. non-cancer) was not associated with a change in survival time (aHR: 1.03; 95 % CI: 0.96–1.10). CONCLUSIONS: In this cross-sectional study, the most relevant predictor for a short survival time in specialized ambulatory palliative care was the performance status while type of disease was irrelevant to survival. BioMed Central 2021-05-17 /pmc/articles/PMC8130350/ /pubmed/34001099 http://dx.doi.org/10.1186/s12904-021-00762-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Just, Johannes
Schmitz, Marie-Therese
Grabenhorst, Ulrich
Joist, Thomas
Horn, Kirsten
Engel, Bettina
Weckbecker, Klaus
Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
title Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
title_full Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
title_fullStr Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
title_full_unstemmed Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
title_short Factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
title_sort factors influencing length of survival in ambulatory palliative care - a cross sectional study based on secondary data
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130350/
https://www.ncbi.nlm.nih.gov/pubmed/34001099
http://dx.doi.org/10.1186/s12904-021-00762-x
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