VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology

V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) is a negative checkpoint regulator (NCR) that is involved in T-cell quiescence, inhibition of T-cell activation, and in myeloid cells regulates cytokine production, chemotaxis, phagocytosis, and tolerance induction. In t...

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Detalles Bibliográficos
Autores principales: Borggrewe, Malte, Kooistra, Susanne M., Wesseling, Evelyn M., Gierschek, Fenja L., Brummer, Maaike L., Nowak, Elizabeth C., Medeiros-Furquim, Tiago, Otto, Tegan A., Lee, Sam W., Noelle, Randolph J., Eggen, Bart J. L., Laman, Jon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130385/
https://www.ncbi.nlm.nih.gov/pubmed/34006329
http://dx.doi.org/10.1186/s40478-021-01186-7

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