Cargando…

Immunotherapy for the prevention of high-risk oral disorders malignant transformation: the IMPEDE trial

BACKGROUND: Oral Potentially Malignant Disorders (OPMD) have a non-negligible malignant transformation rate of up to 8%. Loss of heterozygosity (LOH) in critical chromosomal loci has proven to be the most effective marker in defining the risk of transformation and it is found in about 28% of OPMD an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gurizzan, Cristina, Lorini, Luigi, Paderno, Alberto, Tomasoni, Michele, Zigliani, Gabriele, Bozzola, Anna, Ardighieri, Laura, Battocchio, Simonetta, Bignotti, Eliana, Ravaggi, Antonella, Romani, Chiara, De Cecco, Loris, Serafini, Mara Serena, Miceli, Rosalba, Bardellini, Elena, Majorana, Alessandra, Piazza, Cesare, Bossi, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130439/ https://www.ncbi.nlm.nih.gov/pubmed/34001010 http://dx.doi.org/10.1186/s12885-021-08297-3

Ejemplares similares

Functional profiles of curatively treated adenoid cystic carcinoma unveil prognostic features and potentially targetable pathways
por: Romani, Chiara, et al.
Publicado: (2023)

Clinical and Histological Prognostic Factors of Recurrence and Malignant Transformation in a Large Series of Oral Potentially Malignant Disorders
por: Lorini, Luigi, et al.
Publicado: (2022)

Gene Expression Profiling of Olfactory Neuroblastoma Helps Identify Prognostic Pathways and Define Potentially Therapeutic Targets
por: Romani, Chiara, et al.
Publicado: (2021)

Adenosquamous cell carcinoma of the head and neck: a retrospective single institution series
por: Zigliani, Gabriele, et al.
Publicado: (2023)

Prognostic Nomograms in Oral Squamous Cell Carcinoma: The Negative Impact of Low Neutrophil to Lymphocyte Ratio
por: Mattavelli, Davide, et al.
Publicado: (2019)

Does Reorganization of Clinicopathological Information Improve Prognostic Stratification and Prediction of Chemoradiosensitivity in Sinonasal Carcinomas? A Retrospective Study on 145 Patients
por: Ferrari, Marco, et al.
Publicado: (2022)

Genome-wide study of salivary miRNAs identifies miR-423-5p as promising diagnostic and prognostic biomarker in oral squamous cell carcinoma
por: Romani, Chiara, et al.
Publicado: (2021)

Magnetic resonance imaging to assess cartilage invasion in recurrent laryngeal carcinoma after transoral laser microsurgery
por: Ravanelli, Marco, et al.
Publicado: (2022)

Adolescents and primary herpetic gingivostomatitis: an Italian overview
por: Bardellini, Elena, et al.
Publicado: (2021)

Gene Expression Clustering and Selected Head and Neck Cancer Gene Signatures Highlight Risk Probability Differences in Oral Premalignant Lesions
por: Carenzo, Andrea, et al.
Publicado: (2020)

Editorial: Advances in the Multidisciplinary Management of Oral Cancer
por: Paderno, Alberto, et al.
Publicado: (2021)

VEGF-D Serum Level as a Potential Predictor of Lymph Node Metastasis and Prognosis in Vulvar Squamous Cell Carcinoma Patients
por: Ravaggi, Antonella, et al.
Publicado: (2022)

FXYD5 (Dysadherin) upregulation predicts shorter survival and reveals platinum resistance in high-grade serous ovarian cancer patients
por: Tassi, Renata A., et al.
Publicado: (2019)

Integrated Biomarker Analysis Reveals L1CAM as a Potential Stratification Marker for No Specific Molecular Profile High-Risk Endometrial Carcinoma
por: Ravaggi, Antonella, et al.
Publicado: (2022)

Regional disease in head and neck cutaneous squamous cell carcinoma: the role of primary tumor characteristics and number of nodal metastases
por: Grammatica, Alberto, et al.
Publicado: (2021)

Prediction of Posterior Paraglottic Space and Cricoarytenoid Unit Involvement in Endoscopically T3 Glottic Cancer with Arytenoid Fixation by Magnetic Resonance with Surface Coils
por: Ravanelli, Marco, et al.
Publicado: (2019)

Magnetic resonance diagnosis of laryngeal chondritis after transoral laser microsurgery for laryngeal cancer
por: Cunha, Bruno, et al.
Publicado: (2023)

Not all hematopoietic growth factors are created equal: should we gain information for their use with immunotherapy?
por: Bossi, Paolo, et al.
Publicado: (2021)

Metavariables Resuming Host Immune Features and Nodal Involvement Are Associated with Oncological Outcomes in Oral Cavity Squamous Cell Carcinoma
por: Missale, Francesco, et al.
Publicado: (2021)

Identification of stably expressed reference small non‐coding RNAs for microRNA quantification in high‐grade serous ovarian carcinoma tissues
por: Bignotti, Eliana, et al.
Publicado: (2016)

Pre-treatment Serum HE4 Level as a Novel Independent Prognostic Biomarker for Uterine Cervical Carcinoma Patients
por: Bignotti, Eliana, et al.
Publicado: (2020)

Oral mucosal lesions in teenagers: a cross-sectional study
por: Amadori, Francesca, et al.
Publicado: (2017)

Efficacy of the photobiomodulation therapy in the treatment of the burning mouth syndrome
por: Bardellini, Elena, et al.
Publicado: (2019)

MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis
por: Zanotti, Laura, et al.
Publicado: (2017)

Low Expression of Claudin-7 as Potential Predictor of Distant Metastases in High-Grade Serous Ovarian Carcinoma Patients
por: Romani, Chiara, et al.
Publicado: (2020)

Identification of Optimal Reference Genes for Gene Expression Normalization in a Wide Cohort of Endometrioid Endometrial Carcinoma Tissues
por: Romani, Chiara, et al.
Publicado: (2014)

Instance segmentation of upper aerodigestive tract cancer: site-specific outcomes
por: Paderno, Alberto, et al.
Publicado: (2023)

Cytotoxic effects of targeted agent alone or with chemotherapy in the treatment of adenoid cystic carcinoma: a preclinical study
por: Savarese, Teresa, et al.
Publicado: (2022)

Timetable for oral prevention in childhood—developing dentition and oral habits: a current opinion
por: Majorana, Alessandra, et al.
Publicado: (2015)

Effectiveness of a spray containing 1% malic acid in patients with xerostomia induced by graft-versus-host disease
por: Bardellini, Elena, et al.
Publicado: (2019)

Photobiomodulation therapy for the management of recurrent aphthous stomatitis in children: clinical effectiveness and parental satisfaction
por: Bardellini, Elena, et al.
Publicado: (2020)

Efficacy of ozonized water for the treatment of erosive oral lichen planus: a randomized controlled study
por: Veneri, Federica, et al.
Publicado: (2020)

The Impact of the COVID-19 Pandemic on Pediatric Dentistry: Insights from an Italian Cross-Sectional Survey
por: Conti, Giulio, et al.
Publicado: (2023)

The Claudin-Low Subtype of High-Grade Serous Ovarian Carcinoma Exhibits Stem Cell Features
por: Romani, Chiara, et al.
Publicado: (2021)

Is there any correlation between otitis media and dental malocclusion in children? A systematic review
por: Bardellini, E., et al.
Publicado: (2023)

Large-sized pleomorphic adenoma of the cheek treated with Nd:Yag laser: report of a case and review of the literature
por: Veneri, Federica, et al.
Publicado: (2020)

Evaluation of Antibacterial Activity of a Bioactive Restorative Material Versus a Glass-Ionomer Cement on Streptococcus Mutans: In-Vitro Study
por: Conti, Giulio, et al.
Publicado: (2023)

Infiltration by CXCL10 Secreting Macrophages Is Associated With Antitumor Immunity and Response to Therapy in Ovarian Cancer Subtypes
por: Ardighieri, Laura, et al.
Publicado: (2021)

The HIV-protease inhibitor saquinavir reduces proliferation, invasion and clonogenicity in cervical cancer cell lines
por: Bandiera, Elisabetta, et al.
Publicado: (2016)

Prognostic Significance of Vascular Endothelial Growth Factor Serum Determination in Women with Ovarian Cancer
por: Bandiera, Elisabetta, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_s0hjm9qomlgkpl0rrdn41un8r9