Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?

INTRODUCTION: Amantadine is a well-known medication with indications in neurology and infectious diseases. It is currently FDA approved for Parkinson’s disease, drug-induced extrapyramidal symptoms, and influenza. METHODS: The article is the author’s original research hypothesis. RESULTS: Because mo...

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Detalles Bibliográficos
Autor principal: Fedorowski, Jaroslaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130463/
https://www.ncbi.nlm.nih.gov/pubmed/34025855
http://dx.doi.org/10.5114/aoms/134716
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author Fedorowski, Jaroslaw J.
author_facet Fedorowski, Jaroslaw J.
author_sort Fedorowski, Jaroslaw J.
collection PubMed
description INTRODUCTION: Amantadine is a well-known medication with indications in neurology and infectious diseases. It is currently FDA approved for Parkinson’s disease, drug-induced extrapyramidal symptoms, and influenza. METHODS: The article is the author’s original research hypothesis. RESULTS: Because more people are going to be vaccinated and additional similar vaccines are going to be introduced, we should take into consideration the potential of amantadine to interfere with LNP-mRNA COVID-19 vaccine delivery into the target cells. CONCLUSIONS: A more cautious approach to the patients taking amantadine as far as vaccination utilizing LNP-mRNA platform should be considered.
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spelling pubmed-81304632021-05-21 Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform? Fedorowski, Jaroslaw J. Arch Med Sci Research Letter INTRODUCTION: Amantadine is a well-known medication with indications in neurology and infectious diseases. It is currently FDA approved for Parkinson’s disease, drug-induced extrapyramidal symptoms, and influenza. METHODS: The article is the author’s original research hypothesis. RESULTS: Because more people are going to be vaccinated and additional similar vaccines are going to be introduced, we should take into consideration the potential of amantadine to interfere with LNP-mRNA COVID-19 vaccine delivery into the target cells. CONCLUSIONS: A more cautious approach to the patients taking amantadine as far as vaccination utilizing LNP-mRNA platform should be considered. Termedia Publishing House 2021-03-28 /pmc/articles/PMC8130463/ /pubmed/34025855 http://dx.doi.org/10.5114/aoms/134716 Text en Copyright: © 2021 Termedia & Banach https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Research Letter
Fedorowski, Jaroslaw J.
Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?
title Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?
title_full Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?
title_fullStr Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?
title_full_unstemmed Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?
title_short Could amantadine interfere with COVID-19 vaccines based on the LNP-mRNA platform?
title_sort could amantadine interfere with covid-19 vaccines based on the lnp-mrna platform?
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130463/
https://www.ncbi.nlm.nih.gov/pubmed/34025855
http://dx.doi.org/10.5114/aoms/134716
work_keys_str_mv AT fedorowskijaroslawj couldamantadineinterferewithcovid19vaccinesbasedonthelnpmrnaplatform

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