COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials

Children usually present with milder symptoms of COVID-19 as compared with adults. Supportive care alone is appropriate for most children with COVID-19. Antiviral therapy may be required for those with severe or critical diseases. Currently there has been a rapid development of vaccines globally to...

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Detalles Bibliográficos
Autores principales: Galindo, Ramon, Chow, Heather, Rongkavilit, Chokechai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130516/
https://www.ncbi.nlm.nih.gov/pubmed/34538306
http://dx.doi.org/10.1016/j.pcl.2021.05.004
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author Galindo, Ramon
Chow, Heather
Rongkavilit, Chokechai
author_facet Galindo, Ramon
Chow, Heather
Rongkavilit, Chokechai
author_sort Galindo, Ramon
collection PubMed
description Children usually present with milder symptoms of COVID-19 as compared with adults. Supportive care alone is appropriate for most children with COVID-19. Antiviral therapy may be required for those with severe or critical diseases. Currently there has been a rapid development of vaccines globally to prevent COVID-19 and several vaccines are being evaluated in children and adolescents. Currently, only the Pfizer–BioNTech messenger RNA vaccine is approved for emergency authorization use in the pediatric population ages 16 years and older.
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spelling pubmed-81305162021-05-18 COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials Galindo, Ramon Chow, Heather Rongkavilit, Chokechai Pediatr Clin North Am Article Children usually present with milder symptoms of COVID-19 as compared with adults. Supportive care alone is appropriate for most children with COVID-19. Antiviral therapy may be required for those with severe or critical diseases. Currently there has been a rapid development of vaccines globally to prevent COVID-19 and several vaccines are being evaluated in children and adolescents. Currently, only the Pfizer–BioNTech messenger RNA vaccine is approved for emergency authorization use in the pediatric population ages 16 years and older. Elsevier Inc. 2021-10 2021-05-18 /pmc/articles/PMC8130516/ /pubmed/34538306 http://dx.doi.org/10.1016/j.pcl.2021.05.004 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Galindo, Ramon
Chow, Heather
Rongkavilit, Chokechai
COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials
title COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials
title_full COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials
title_fullStr COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials
title_full_unstemmed COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials
title_short COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials
title_sort covid-19 in children: clinical manifestations and pharmacologic interventions including vaccine trials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130516/
https://www.ncbi.nlm.nih.gov/pubmed/34538306
http://dx.doi.org/10.1016/j.pcl.2021.05.004
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