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Complications in COVID-19 patients: Characteristics of pulmonary embolism

OBJECTIVE: The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a...

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Autores principales: Cau, Riccardo, Pacielli, Alberto, Fatemeh, Homayounieh, Vaudano, Paolo, Arru, Chiara, Crivelli, Paola, Stranieri, Giuseppe, Suri, Jasjit S., Mannelli, Lorenzo, Conti, Maurizio, Mahammedi, Abdelkader, Kalra, Mannudeep, Saba, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130594/
https://www.ncbi.nlm.nih.gov/pubmed/34029929
http://dx.doi.org/10.1016/j.clinimag.2021.05.016
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author Cau, Riccardo
Pacielli, Alberto
Fatemeh, Homayounieh
Vaudano, Paolo
Arru, Chiara
Crivelli, Paola
Stranieri, Giuseppe
Suri, Jasjit S.
Mannelli, Lorenzo
Conti, Maurizio
Mahammedi, Abdelkader
Kalra, Mannudeep
Saba, Luca
author_facet Cau, Riccardo
Pacielli, Alberto
Fatemeh, Homayounieh
Vaudano, Paolo
Arru, Chiara
Crivelli, Paola
Stranieri, Giuseppe
Suri, Jasjit S.
Mannelli, Lorenzo
Conti, Maurizio
Mahammedi, Abdelkader
Kalra, Mannudeep
Saba, Luca
author_sort Cau, Riccardo
collection PubMed
description OBJECTIVE: The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a higher rate of PE. MATERIALS AND METHODS: This retrospective study included 84 consecutive patients with laboratory-confirmed SARS-CoV-2 who underwent CTA for suspected PE. The presence and localization of PE as well as the type and extent of pulmonary opacities on chest CT exams were examined and correlated with the information on comorbidities and laboratory values for all patients. RESULTS: Of the 84 patients, pulmonary embolism was discovered in 24 patients. We observed that 87% of PE was found to be in lung parenchyma affected by COVID-19 pneumonia. Compared with no-PE patients, PE patients showed an overall greater lung involvement by consolidation (p = 0.02) and GGO (p < 0.01) and a higher level of D-Dimer (p < 0,01). Moreover, the PE group showed a lower level of saturation (p = 0,01) and required more hospitalization (p < 0,01). CONCLUSION: Our study showed a high incidence of PE in COVID-19 pneumonia. In 87% of patients, PE was found in lung parenchyma affected by COVID-19 pneumonia with a worse CT severity score and a greater number of lung lobar involvement compared with non-PE patients. CT severity, lower level of saturation, and a rise in D-dimer levels could be an indication for a CTPA. ADVANCES IN KNOWLEDGE: Certain findings of non-contrast chest CT could be an indication for a CTPA.
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spelling pubmed-81305942021-05-18 Complications in COVID-19 patients: Characteristics of pulmonary embolism Cau, Riccardo Pacielli, Alberto Fatemeh, Homayounieh Vaudano, Paolo Arru, Chiara Crivelli, Paola Stranieri, Giuseppe Suri, Jasjit S. Mannelli, Lorenzo Conti, Maurizio Mahammedi, Abdelkader Kalra, Mannudeep Saba, Luca Clin Imaging Cardiothoracic Imaging OBJECTIVE: The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a higher rate of PE. MATERIALS AND METHODS: This retrospective study included 84 consecutive patients with laboratory-confirmed SARS-CoV-2 who underwent CTA for suspected PE. The presence and localization of PE as well as the type and extent of pulmonary opacities on chest CT exams were examined and correlated with the information on comorbidities and laboratory values for all patients. RESULTS: Of the 84 patients, pulmonary embolism was discovered in 24 patients. We observed that 87% of PE was found to be in lung parenchyma affected by COVID-19 pneumonia. Compared with no-PE patients, PE patients showed an overall greater lung involvement by consolidation (p = 0.02) and GGO (p < 0.01) and a higher level of D-Dimer (p < 0,01). Moreover, the PE group showed a lower level of saturation (p = 0,01) and required more hospitalization (p < 0,01). CONCLUSION: Our study showed a high incidence of PE in COVID-19 pneumonia. In 87% of patients, PE was found in lung parenchyma affected by COVID-19 pneumonia with a worse CT severity score and a greater number of lung lobar involvement compared with non-PE patients. CT severity, lower level of saturation, and a rise in D-dimer levels could be an indication for a CTPA. ADVANCES IN KNOWLEDGE: Certain findings of non-contrast chest CT could be an indication for a CTPA. Elsevier Inc. 2021-09 2021-05-18 /pmc/articles/PMC8130594/ /pubmed/34029929 http://dx.doi.org/10.1016/j.clinimag.2021.05.016 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Cardiothoracic Imaging
Cau, Riccardo
Pacielli, Alberto
Fatemeh, Homayounieh
Vaudano, Paolo
Arru, Chiara
Crivelli, Paola
Stranieri, Giuseppe
Suri, Jasjit S.
Mannelli, Lorenzo
Conti, Maurizio
Mahammedi, Abdelkader
Kalra, Mannudeep
Saba, Luca
Complications in COVID-19 patients: Characteristics of pulmonary embolism
title Complications in COVID-19 patients: Characteristics of pulmonary embolism
title_full Complications in COVID-19 patients: Characteristics of pulmonary embolism
title_fullStr Complications in COVID-19 patients: Characteristics of pulmonary embolism
title_full_unstemmed Complications in COVID-19 patients: Characteristics of pulmonary embolism
title_short Complications in COVID-19 patients: Characteristics of pulmonary embolism
title_sort complications in covid-19 patients: characteristics of pulmonary embolism
topic Cardiothoracic Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130594/
https://www.ncbi.nlm.nih.gov/pubmed/34029929
http://dx.doi.org/10.1016/j.clinimag.2021.05.016
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