Cargando…
Complications in COVID-19 patients: Characteristics of pulmonary embolism
OBJECTIVE: The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130594/ https://www.ncbi.nlm.nih.gov/pubmed/34029929 http://dx.doi.org/10.1016/j.clinimag.2021.05.016 |
_version_ | 1783694557114793984 |
---|---|
author | Cau, Riccardo Pacielli, Alberto Fatemeh, Homayounieh Vaudano, Paolo Arru, Chiara Crivelli, Paola Stranieri, Giuseppe Suri, Jasjit S. Mannelli, Lorenzo Conti, Maurizio Mahammedi, Abdelkader Kalra, Mannudeep Saba, Luca |
author_facet | Cau, Riccardo Pacielli, Alberto Fatemeh, Homayounieh Vaudano, Paolo Arru, Chiara Crivelli, Paola Stranieri, Giuseppe Suri, Jasjit S. Mannelli, Lorenzo Conti, Maurizio Mahammedi, Abdelkader Kalra, Mannudeep Saba, Luca |
author_sort | Cau, Riccardo |
collection | PubMed |
description | OBJECTIVE: The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a higher rate of PE. MATERIALS AND METHODS: This retrospective study included 84 consecutive patients with laboratory-confirmed SARS-CoV-2 who underwent CTA for suspected PE. The presence and localization of PE as well as the type and extent of pulmonary opacities on chest CT exams were examined and correlated with the information on comorbidities and laboratory values for all patients. RESULTS: Of the 84 patients, pulmonary embolism was discovered in 24 patients. We observed that 87% of PE was found to be in lung parenchyma affected by COVID-19 pneumonia. Compared with no-PE patients, PE patients showed an overall greater lung involvement by consolidation (p = 0.02) and GGO (p < 0.01) and a higher level of D-Dimer (p < 0,01). Moreover, the PE group showed a lower level of saturation (p = 0,01) and required more hospitalization (p < 0,01). CONCLUSION: Our study showed a high incidence of PE in COVID-19 pneumonia. In 87% of patients, PE was found in lung parenchyma affected by COVID-19 pneumonia with a worse CT severity score and a greater number of lung lobar involvement compared with non-PE patients. CT severity, lower level of saturation, and a rise in D-dimer levels could be an indication for a CTPA. ADVANCES IN KNOWLEDGE: Certain findings of non-contrast chest CT could be an indication for a CTPA. |
format | Online Article Text |
id | pubmed-8130594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81305942021-05-18 Complications in COVID-19 patients: Characteristics of pulmonary embolism Cau, Riccardo Pacielli, Alberto Fatemeh, Homayounieh Vaudano, Paolo Arru, Chiara Crivelli, Paola Stranieri, Giuseppe Suri, Jasjit S. Mannelli, Lorenzo Conti, Maurizio Mahammedi, Abdelkader Kalra, Mannudeep Saba, Luca Clin Imaging Cardiothoracic Imaging OBJECTIVE: The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a higher rate of PE. MATERIALS AND METHODS: This retrospective study included 84 consecutive patients with laboratory-confirmed SARS-CoV-2 who underwent CTA for suspected PE. The presence and localization of PE as well as the type and extent of pulmonary opacities on chest CT exams were examined and correlated with the information on comorbidities and laboratory values for all patients. RESULTS: Of the 84 patients, pulmonary embolism was discovered in 24 patients. We observed that 87% of PE was found to be in lung parenchyma affected by COVID-19 pneumonia. Compared with no-PE patients, PE patients showed an overall greater lung involvement by consolidation (p = 0.02) and GGO (p < 0.01) and a higher level of D-Dimer (p < 0,01). Moreover, the PE group showed a lower level of saturation (p = 0,01) and required more hospitalization (p < 0,01). CONCLUSION: Our study showed a high incidence of PE in COVID-19 pneumonia. In 87% of patients, PE was found in lung parenchyma affected by COVID-19 pneumonia with a worse CT severity score and a greater number of lung lobar involvement compared with non-PE patients. CT severity, lower level of saturation, and a rise in D-dimer levels could be an indication for a CTPA. ADVANCES IN KNOWLEDGE: Certain findings of non-contrast chest CT could be an indication for a CTPA. Elsevier Inc. 2021-09 2021-05-18 /pmc/articles/PMC8130594/ /pubmed/34029929 http://dx.doi.org/10.1016/j.clinimag.2021.05.016 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Cardiothoracic Imaging Cau, Riccardo Pacielli, Alberto Fatemeh, Homayounieh Vaudano, Paolo Arru, Chiara Crivelli, Paola Stranieri, Giuseppe Suri, Jasjit S. Mannelli, Lorenzo Conti, Maurizio Mahammedi, Abdelkader Kalra, Mannudeep Saba, Luca Complications in COVID-19 patients: Characteristics of pulmonary embolism |
title | Complications in COVID-19 patients: Characteristics of pulmonary embolism |
title_full | Complications in COVID-19 patients: Characteristics of pulmonary embolism |
title_fullStr | Complications in COVID-19 patients: Characteristics of pulmonary embolism |
title_full_unstemmed | Complications in COVID-19 patients: Characteristics of pulmonary embolism |
title_short | Complications in COVID-19 patients: Characteristics of pulmonary embolism |
title_sort | complications in covid-19 patients: characteristics of pulmonary embolism |
topic | Cardiothoracic Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130594/ https://www.ncbi.nlm.nih.gov/pubmed/34029929 http://dx.doi.org/10.1016/j.clinimag.2021.05.016 |
work_keys_str_mv | AT cauriccardo complicationsincovid19patientscharacteristicsofpulmonaryembolism AT paciellialberto complicationsincovid19patientscharacteristicsofpulmonaryembolism AT fatemehhomayounieh complicationsincovid19patientscharacteristicsofpulmonaryembolism AT vaudanopaolo complicationsincovid19patientscharacteristicsofpulmonaryembolism AT arruchiara complicationsincovid19patientscharacteristicsofpulmonaryembolism AT crivellipaola complicationsincovid19patientscharacteristicsofpulmonaryembolism AT stranierigiuseppe complicationsincovid19patientscharacteristicsofpulmonaryembolism AT surijasjits complicationsincovid19patientscharacteristicsofpulmonaryembolism AT mannellilorenzo complicationsincovid19patientscharacteristicsofpulmonaryembolism AT contimaurizio complicationsincovid19patientscharacteristicsofpulmonaryembolism AT mahammediabdelkader complicationsincovid19patientscharacteristicsofpulmonaryembolism AT kalramannudeep complicationsincovid19patientscharacteristicsofpulmonaryembolism AT sabaluca complicationsincovid19patientscharacteristicsofpulmonaryembolism |