Discrepancy between Multiparametric Magnetic Resonance Imaging and (68)Ga Prostate-Specific Membrane Antigen Positron Emission Tomography: A Simultaneous Acquired Positron Emission Tomography-Magnetic Resonance Imaging Case

Conventionally, multiparametric magnetic resonance imaging (mpMRI) incorporating T2-weighted, diffusion-weighted, and dynamic contrast-enhanced sequences is considered the standard for detection and staging of clinically important prostate cancer (PCa).[1] The (68)gallium ((68)Ga)-labeled positron emission tomography (PET) tracer targeting prostate-specific membrane antigen (PSMA), (68)Ga-PSMA PET, is a promising tool for detection, localization, and staging carcinoma prostate.[2] Here, we present a case of PCa, showing incongruence between (68)Ga-PSMA PET and the corresponding mpMRI findings. Moreover, the final histopathology revealed a surprise, which exemplifies the complementary nature of combining (68)Ga-PSMA PET and mpMRI in the diagnosis and staging of carcinoma prostate.