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Characterization of a Trpc6 Transgenic Mouse Associated with Early Onset FSGS

RATIONALE: Mutations in Transient Receptor Potential Channel 6 (TRPC6) gene are associated with autosomal dominant focal and segmental glomerulosclerosis (FSGS). The majority of the identified mutations affect the ion channel function. Since calcium channels are promising candidate drug targets, the...

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Detalles Bibliográficos
Autores principales:	Canales, Cesar P., Krall, Paola, Kairath, Pamela, Perez, Irene C., Fragoso, Miryam A., Carmona-Mora, Paulina, Ruiz, Phillip, Reiser, Jochen, Young, Juan I., Walz, Katherina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130885/ https://www.ncbi.nlm.nih.gov/pubmed/34012910 http://dx.doi.org/10.9734/bjmmr/2015/12493

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