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EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape

The Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the impact of EBV miRNAs on remodeling the tumor cell transcriptome. Strikingly, EBV miRNAs displayed exceptionally abundant expr...

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Detalles Bibliográficos
Autores principales: Ungerleider, Nathan, Bullard, Whitney, Kara, Mehmet, Wang, Xia, Roberts, Claire, Renne, Rolf, Tibbetts, Scott, Flemington, Erik K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130916/
https://www.ncbi.nlm.nih.gov/pubmed/33956915
http://dx.doi.org/10.1371/journal.ppat.1009217