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HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

Eukaryotic cells use guided search to coordinately control dispersed genetic elements. Argonaute proteins and their small RNA cofactors engage nascent RNAs and chromatin-associated proteins to direct transcriptional silencing. The small ubiquitin-like modifier (SUMO) has been shown to promote the fo...

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Detalles Bibliográficos
Autores principales: Kim, Heesun, Ding, Yue-He, Zhang, Gangming, Yan, Yong-Hong, Conte, Darryl, Dong, Meng-Qiu, Mello, Craig C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131101/
https://www.ncbi.nlm.nih.gov/pubmed/34003109
http://dx.doi.org/10.7554/eLife.63299